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创伤性脊髓损伤中细胞移植的研究热点与趋势分析:文献计量学与可视化分析

Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis.

作者信息

Guo Yuhuai, Gao Bowen, Sun Shilin, Li Jianuo, Lv Xiaolin, Yin Hongna, Sun Zhongren, Cai Shuo

机构信息

Department of TCM, Guangzhou Women and Children's Medical Center of Guangzhou Medical University, Guangzhou, China.

The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Front Pharmacol. 2023 Dec 11;14:1326583. doi: 10.3389/fphar.2023.1326583. eCollection 2023.


DOI:10.3389/fphar.2023.1326583
PMID:38161703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10755575/
Abstract

A traumatic spinal cord injury (TSCI) can lead to severe nerve damage and disability. Cell transplantation therapy has shown great potential in the reconstruction of damaged spinal cords and promoting functional recovery. However, there is a lack of frontiers and futures analysis in the study of cell transplantation in TSCI. We used CiteSpace, VOSviewer and biblilometrix R package to perform bibliometric analysis on cell transplantation in TSCI from 2013 to 2023. Bibliometric records were extracted from English articles and reviews from the Web of Science core collection. The bibliometric analysis included 284 papers published in 154 journals by 1,780 authors from 487 institutions in 41 countries and regions. The number of articles published in the past decade has fluctuated slightly, while the number of article citations has steadily increased. Mainland China and the United States are the leading countries and regions in this field, with the National Natural Science Foundation of China being the most funded foundation, and the United States being the country with the most funded articles. The University of Toronto in Canada is a prolific institution. Michael G. Fehlings has published the most articles, and D Michele Basso is the most cited author. is the most published journal, and is the most cited journal. Cell and tissue engineering and clinical neurology are the basic disciplines in this field, and cutting-edge disciplines include developmental biology, biochemistry and molecular biology, and materials science and multidisciplinary. This study also helps scholars understand the current hotspots and future trends in this field. Marrow stromal cells, glial progenitor, and cell therapy are current research hotspots in this field, while nerve regeneration, cell therapy, and the safety of transplantation of transplantation may be potential research directions in the future. Cell transplantation after TSCI is receiving increasing attention. Cell therapy is both the frontier and a possible future trend in TSCI research. In addition, glial progenitor and marrow stromal cells are also current research hotspots. Meanwhile, nerve regeneration and safety of transplantation may be potential research directions. These findings will help further deepen research on cell transplantation for TSCI in scientific work.

摘要

创伤性脊髓损伤(TSCI)可导致严重的神经损伤和残疾。细胞移植疗法在受损脊髓重建和促进功能恢复方面显示出巨大潜力。然而,TSCI细胞移植研究缺乏前沿和未来分析。我们使用CiteSpace、VOSviewer和biblilometrix R包对2013年至2023年TSCI细胞移植进行文献计量分析。文献计量记录从Web of Science核心合集中的英文文章和综述中提取。文献计量分析包括来自41个国家和地区487个机构的1780名作者在154种期刊上发表的284篇论文。过去十年发表的文章数量略有波动,而文章被引次数稳步增加。中国大陆和美国是该领域的主要国家和地区,中国国家自然科学基金是资助最多的基金,美国是资助文章最多的国家。加拿大多伦多大学是多产机构。迈克尔·G·费林斯发表的文章最多,D·米歇尔·巴索是被引次数最多的作者。 是发表文章最多的期刊, 是被引次数最多的期刊。细胞与组织工程和临床神经学是该领域的基础学科,前沿学科包括发育生物学、生物化学与分子生物学、材料科学与多学科。本研究还有助于学者了解该领域当前的热点和未来趋势。骨髓基质细胞、神经胶质祖细胞和细胞疗法是该领域当前的研究热点,而神经再生、细胞疗法和移植安全性可能是未来潜在的研究方向。TSCI后的细胞移植正受到越来越多的关注。细胞疗法既是TSCI研究的前沿,也是可能的未来趋势。此外,神经胶质祖细胞和骨髓基质细胞也是当前的研究热点。同时,神经再生和移植安全性可能是潜在的研究方向。这些发现将有助于在科研工作中进一步深化对TSCI细胞移植的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/d7b3041bc8be/fphar-14-1326583-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/6cf713898a37/fphar-14-1326583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/8864adef43c3/fphar-14-1326583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/16a3ec9280df/fphar-14-1326583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/d7b3041bc8be/fphar-14-1326583-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/6cf713898a37/fphar-14-1326583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/8864adef43c3/fphar-14-1326583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/16a3ec9280df/fphar-14-1326583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/911b/10755575/d7b3041bc8be/fphar-14-1326583-g004.jpg

相似文献

[1]
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis.

Front Pharmacol. 2023-12-11

[2]
Bibliometric analysis of stem cells for spinal cord injury: current status and emerging frontiers.

Front Pharmacol. 2023-7-18

[3]
A bibliometric analysis of the research hotspots and frontiers related to cell death in spinal cord injury.

Front Neurol. 2024-1-5

[4]
Bibliometric and Visualized Analysis of Stem Cells Therapy for Spinal Cord Injury Based on Web of Science and CiteSpace in the Last 20 Years.

World Neurosurg. 2019-9-4

[5]
Olfactory ensheathing cell transplantation for spinal cord injury: An 18-year bibliometric analysis based on the Web of Science.

Neural Regen Res. 2013-5-15

[6]
Knowledge domain and hotspots concerning photosensitive hydrogels for tissue engineering applications: A bibliometric and visualized analysis (1996-2022).

Front Bioeng Biotechnol. 2022-11-14

[7]
Worldwide productivity and research trend of publications concerning electroactive materials and spinal cord injury: A bibliometric study.

Front Bioeng Biotechnol. 2023-2-27

[8]
Articles on hemorrhagic shock published between 2000 and 2021: A CiteSpace-Based bibliometric analysis.

Heliyon. 2023-8-7

[9]
Hotspot Analysis and Frontier Exploration of Stem Cell Research in Intervertebral Disc Regeneration and Repair: A Bibliometric and Visualization Study.

World Neurosurg. 2024-4

[10]
Research Hotspots and Trends of Peripheral Nerve Injuries Based on Web of Science From 2017 to 2021: A Bibliometric Analysis.

Front Neurol. 2022-5-20

本文引用的文献

[1]
Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances.

Brain. 2024-3-1

[2]
Prevalence, Incidence, and External Causes of Traumatic Spinal Cord Injury in China: A Nationally Representative Cross-Sectional Survey.

Front Neurol. 2022-1-20

[3]
Will COVID-19 result in a giant step backwards for women in academic science?

J Clin Epidemiol. 2021-6

[4]
Leveling the Playing Field: Accounting for Academic Productivity During the COVID-19 Pandemic.

J Hosp Med. 2021-2

[5]
Citation bias and other determinants of citation in biomedical research: findings from six citation networks.

J Clin Epidemiol. 2021-4

[6]
A Bibliometric Analysis of Publications on Spinal Cord Injury During 1980-2018.

World Neurosurg. 2020-4

[7]
The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury.

Glia. 2019-8-21

[8]
Mesenchymal Stem Cells for Spinal Cord Injury: Current Options, Limitations, and Future of Cell Therapy.

Int J Mol Sci. 2019-5-31

[9]
Spinal cord injury: pathophysiology, treatment strategies, associated challenges, and future implications.

Cell Tissue Res. 2019-5-7

[10]
Intraspinal Delivery of Schwann Cells for Spinal Cord Injury.

Methods Mol Biol. 2018

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