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伴有肠化生的尿道肉阜:一例报告及文献复习

Urethral caruncle with intestinal metaplasia: A case report and literature review.

作者信息

Hanna Bishoy, Hanna Amir, Wines Michael

机构信息

Northern Beaches Hospital, 105 Frenchs Forest Rd W, Frenchs Forest, NSW, 2086, Australia.

Department of Obstetrics and Gynaecology, Sydney Adventist Hospital, 185 Fox Valley Rd, Wahroonga, NSW, 2076, Australia.

出版信息

Urol Case Rep. 2020 Jan 9;30:101114. doi: 10.1016/j.eucr.2020.101114. eCollection 2020 May.

DOI:10.1016/j.eucr.2020.101114
PMID:31956512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6961171/
Abstract

A 66-year-old female presented with a urethral caruncle. Histological features of incomplete intestinal metaplasia were reported. Only five previous cases of intestinal metaplasia in urethral caruncles have been reported. The mechanism of this tissue transformation remains unclear but theorised aetiologies include embryological and infective causes. Intestinal metaplasia carries a malignant potential in other organs, most notably the bladder. Therefore we recommend urethral caruncles be completely excised with prolonged follow up for atypical variants.

摘要

一名66岁女性因尿道肉阜就诊。报告显示有不完全肠化生的组织学特征。此前仅报道过5例尿道肉阜发生肠化生的病例。这种组织转化的机制尚不清楚,但推测的病因包括胚胎学和感染性原因。肠化生在其他器官,最显著的是膀胱,具有恶变潜能。因此,我们建议将尿道肉阜完整切除,并对非典型变体进行长期随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84dd/6961171/840747c572d4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84dd/6961171/ee09a26cbacb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84dd/6961171/840747c572d4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84dd/6961171/ee09a26cbacb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84dd/6961171/840747c572d4/gr2.jpg

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1
Urethral caruncle with intestinal metaplasia: A case report and literature review.伴有肠化生的尿道肉阜:一例报告及文献复习
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本文引用的文献

1
Intestinal metaplasia of the bladder in 89 patients: a study with emphasis on long-term outcome.89例膀胱肠化生患者的研究:一项着重于长期预后的研究
BMC Urol. 2016 Jun 7;16(1):24. doi: 10.1186/s12894-016-0142-x.
2
Polypoidal intestinal metaplasia and dysplasia of the external urethral meatus.息肉样肠化生及尿道外口发育异常
Case Rep Nephrol. 2012;2012:703908. doi: 10.1155/2012/703908. Epub 2012 Dec 24.
3
Letter: Intestinal heterotopia in urethral caruncle.信件:尿道肉阜中的肠化生。
Dermatol Online J. 2012 Jul 15;18(7):13.
4
Mucinous urethral caruncle.黏液性尿道肉阜
Urology. 1978 Nov;12(5):587-90. doi: 10.1016/0090-4295(78)90481-8.