Department of Cardiology, Dunedin Hospital, Dunedin, New Zealand.
Biostatistics Unit, Office of the Dean, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Heart Lung Circ. 2020 Aug;29(8):1187-1194. doi: 10.1016/j.hlc.2019.10.007. Epub 2019 Dec 5.
Cardiac surgery risk scoring systems predict operative mortality but not outcomes related to preoperative frailty. The aim of this study was to assess frailty in a cohort of older cardiac surgery patients as a predictor of postoperative outcomes.
Prospective data was collected on patients 65 years of age and older undergoing cardiac surgery between September 2015 and October 2016 at Dunedin Hospital. Frailty was assessed with the Edmonton frail scale and five-metre gait speed. The primary endpoint was length of hospital stay. Secondary outcomes included postoperative complications, major adverse events, death and 12-month readmission rate.
Among the 96 patients, median age was 74 (interquartile range 10.5) and 65 (68%) were males. Of the sample 64 (67%) were scored as not frail, 22 (23%) as vulnerable, and 10 (10%) as frail. The median (interquartile range) postoperative days' stay were: not frail 6 (2), vulnerable 9.5 (8), and frail 15 (13). Survival analysis adjusting for EuroSCORE II, age, sex and surgery type showed that greater Edmonton Frail Scale scores were independently predictive of longer post-surgery hospital stay with a hazard ratio for discharge of 0.83 (95% confidence interval 0.76-0.91, p<0.001) per point. The Edmonton Frail Scale score was associated with the 12-month post discharge number of readmissions (adjusted incidence rate ratio 1.24 (95% confidence interval 1.13-1.37, p<0.001) per point.
The Edmonton Frail Scale score predicts length of hospital stay post cardiac surgery and 12-month readmission rate in patients older than 65 years of age.
心脏手术风险评分系统可预测手术死亡率,但不能预测与术前虚弱相关的结果。本研究旨在评估老年心脏手术患者队列中的虚弱程度,作为术后结果的预测指标。
2015 年 9 月至 2016 年 10 月,在达尼丁医院对 65 岁及以上接受心脏手术的患者进行了前瞻性数据收集。使用埃德蒙顿虚弱量表和 5 米步行速度评估虚弱程度。主要终点是住院时间。次要结果包括术后并发症、主要不良事件、死亡和 12 个月再入院率。
在 96 例患者中,中位年龄为 74 岁(四分位距 10.5),65 例(68%)为男性。在样本中,64 例(67%)评分不虚弱,22 例(23%)评分脆弱,10 例(10%)评分虚弱。无虚弱组、脆弱组和虚弱组的术后中位(四分位距)住院天数分别为:6(2)、9.5(8)和 15(13)天。对 EuroSCORE II、年龄、性别和手术类型进行调整的生存分析显示,Edmonton 虚弱量表评分越高,术后住院时间越长,出院风险比为 0.83(95%置信区间 0.76-0.91,p<0.001)。Edmonton 虚弱量表评分与 12 个月后出院再入院人数相关(调整后发病率比 1.24(95%置信区间 1.13-1.37,p<0.001)/分)。
Edmonton 虚弱量表评分可预测 65 岁以上患者心脏手术后的住院时间和 12 个月的再入院率。