Department of Ophthalmology Stein Eye Institute, David Geffen School of Medicine at UCLA , Los Angeles, CA, USA.
Department of Ophthalmology, Faculty of Medical and Health Sciences, University of Auckland , Auckland, New Zealand.
Ocul Immunol Inflamm. 2020 Oct 2;28(7):1085-1093. doi: 10.1080/09273948.2019.1704024. Epub 2020 Jan 21.
: To review the broad spectrum of clinical neuro-ophthalmic presentations associated with human immunodeficiency virus (HIV) infection. : Critical review of the literature regarding neuro-ophthalmic consequences of HIV infection and its sequelae. : Neuro-ophthalmological diseases are common in both asymptomatic HIV-positive patients and those who profound immunosuppression with acquired immune deficiency syndrome (AIDS). Neuro-ophthalmic manifestations of HIV infection can involve the afferent or efferent visual pathway. Common clinical presentations include headache, papilledema, chorioretinitis, optic nerve involvement, meningitis, and cranial nerve palsies. Other neuro-ophthalmic manifestations include involvement of the visual pathway in the brain producing visual field defects such as occur in progressive multifocal encephalopathy. Pupil abnormalities have also been reported. : Neuro-ophthalmic consequences of HIV are important to recognize as it is critical to identify underlying neoplastic or infectious diseases which could be amenable to treatment.
: 综述与人类免疫缺陷病毒（HIV）感染相关的广泛的临床神经眼科表现。: 对 HIV 感染及其后遗症的神经眼科后果的文献进行批判性回顾。: 神经眼科疾病在无症状 HIV 阳性患者和患有获得性免疫缺陷综合征（AIDS）的严重免疫抑制患者中都很常见。HIV 感染的神经眼科表现可涉及传入或传出视觉通路。常见的临床表现包括头痛、视盘水肿、脉络膜炎、视神经受累、脑膜炎和颅神经麻痹。其他神经眼科表现包括大脑视觉通路受累导致的视野缺陷，如进行性多灶性脑白质病中发生的那样。也有报道称瞳孔异常。: HIV 的神经眼科后果很重要，因为识别潜在的可治疗的肿瘤或感染性疾病至关重要。
