流行性视网膜炎伴黄斑水肿-有/无类固醇治疗结果。

Epidemic Retinitis with Macular Edema -Treatment Outcome with and without Steroids.

机构信息

Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, India.

Vitreo Retina, Narayana Nethralaya, Bangalore, India.

出版信息

Ocul Immunol Inflamm. 2021 Jul 4;29(5):932-936. doi: 10.1080/09273948.2019.1704792. Epub 2020 Jan 21.

DOI:10.1080/09273948.2019.1704792

PMID:31961210

Abstract

: To study treatment outcomes with and without oral corticosteroids in epidemic retinitis (ER).: A retrospective, observational study of 35 eyes of 29 patients diagnosed as ER. Days taken for resolution of macular edema and retinitis lesions were compared in patients treated with oral antibiotics (Group 1) and with corticosteroids-antibiotics combination (Group 2).: Eighteen eyes of 14 patients and 17 eyes of 15 patients formed Groups 1 and 2, respectively. At the presentation, mean best-corrected visual acuity (BCVA) was 40 and 44 letters and mean central macular thickness was 648 (±243) and 626 (±256) microns in Groups 1 and 2, respectively. Macular edema resolved in 30.83 and 31.94 days; retinitis lesions resolved in 36.71 and 41.41 days in Groups 1 and 2, respectively. BCVA improved to 74 and 77 letters in Groups 1 and 2, respectively.: ER with macular edema can be well managed without corticosteroids.

摘要

: 研究伴有和不伴有口服皮质类固醇的流行视网膜病变（ER）的治疗结果。: 对 29 名患者的 35 只眼诊断为 ER 的回顾性观察性研究。比较了仅用口服抗生素治疗的患者（第 1 组）和用皮质类固醇-抗生素联合治疗的患者（第 2 组）中黄斑水肿和视网膜病变消退的天数。: 第 1 组和第 2 组分别有 14 名患者的 18 只眼和 15 名患者的 17 只眼。在就诊时，第 1 组和第 2 组的平均最佳矫正视力（BCVA）分别为 40 和 44 个字母，平均中央黄斑厚度分别为 648（±243）和 626（±256）微米。第 1 组和第 2 组的黄斑水肿分别在 30.83 和 31.94 天消退，视网膜病变分别在 36.71 和 41.41 天消退。第 1 组和第 2 组的 BCVA 分别提高到 74 和 77 个字母。: ER 合并黄斑水肿可以在不使用皮质类固醇的情况下得到很好的治疗。