Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India.
Department of Vitreo-retina, Narayana Nethralaya, Bangalore, Karnataka, India.
Indian J Ophthalmol. 2022 Mar;70(3):897-901. doi: 10.4103/ijo.IJO_1153_21.
To identify factors other than macular edema and retinitis location responsible for poor visual outcomes in epidemic retinitis (ER).
A.
retrospective, observational, comparative study. Eyes with corrected distant visual acuity (CDVA) 20/200 or worse at resolution formed Group A. Eyes with central macular thickness (CMT) 600 μm or worse and retinitis within 1500 μm to foveal center at the presentation, but improved to CDVA 20/200 or better at the resolution formed Group B. The patient's history, clinical presentation, imaging, and treatment outcomes were studied and the factors responsible for the final visual outcomes were compared in both groups.
Groups A and B included 25 eyes each. The mean CDVA at the presentation was 20/400 (range: 20/125-20000) and 20/320 (range: 20/80-20000), and mean CMT at the presentation was 948.5 μm (range: 520-1553) and 912.2 μm (range: 615-1250) in Groups A and B, respectively. All eyes except 1 (Group A) had retinitis lesions within 1500 μm of foveal center. The mean CDVA at the resolution was 20/400 (range: 20/200-20/20000) and 20/40 (range: 20/20-20/80) in Groups A and B, respectively. Older age, male gender, diabetic status, delayed presentation, poor presenting CDVA, bilaterality, presence of keratic precipitates, disk pallor, retinal thinning, and subfoveal deposits had a statistically significant association, whereas the absence of skin rash, ellipsoid zone loss, negative WIDAL, Weil-Felix test, and delayed doxycycline therapy or use of steroids without doxycycline had a statistically insignificant association with poor visual outcomes.
Apart from presenting CMT and location of retinitis, multiple demographic, clinical, and imaging factors can be implicated for poor visual outcomes.
确定除黄斑水肿和视网膜炎位置以外的因素，这些因素导致流行型视网膜炎（ER）的视觉预后不良。
A.
回顾性、观察性、比较研究。在解决时校正后的远视力（CDVA）为 20/200 或更差的眼睛形成 A 组。在解决时 CDVA 为 20/200 或更好，而在解决时中央黄斑厚度（CMT）为 600μm 或更差，视网膜炎位于中心 1500μm 至中心凹的眼睛形成 B 组。研究了患者的病史、临床表现、影像学和治疗结果，并比较了两组中导致最终视觉结果的因素。
A 组和 B 组各包括 25 只眼睛。在介绍时，平均 CDVA 为 20/400（范围：20/125-20000）和 20/320（范围：20/80-20000），在介绍时平均 CMT 为 948.5μm（范围：520-1553）和 912.2μm（范围：615-1250）在 A 组和 B 组中，分别。除 1 只眼（A 组）外，所有眼的视网膜炎病变均位于中心凹 1500μm 内。在解决时，平均 CDVA 为 20/400（范围：20/200-20/20000）和 20/40（范围：20/20-20/80）在 A 组和 B 组中，分别。年龄较大、男性、糖尿病状态、延迟就诊、较差的就诊 CDVA、双侧性、角膜后沉着物、盘状苍白、视网膜变薄和黄斑下沉积具有统计学显著相关性，而无皮疹、椭圆体带丢失、WIDAL 阴性、魏尔菲克斯试验、以及未及时使用强力霉素或在未使用强力霉素的情况下使用类固醇与视觉预后不良无统计学显著相关性。
除了表现出的 CMT 和视网膜炎位置外，多种人口统计学、临床和影像学因素也可能与视觉预后不良有关。
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