Voshchanova N P, Sokolov L K, Zakharov P I
Arkh Patol. 1988;50(8):52-6.
Cancer involvement of the stomach diagnosed in 225 patients appeared limited to tela submucosa in 252 cases and mucosa in 64.5% of cases. Early diagnosis of metachromatic postoperative cancer was established in 7.6% of patients. Macroscopic forms of the tumors varied. Adenocarcinoma prevailed histologically, its well-differentiated forms occurring in superficial twice as often as in invasive cancer. In 71.8% of patients tumor growth was accompanied by epithelial dysplasia varying in degree. Severe dysplasia was more common in superficial cancer. Carcinomas of exclusively mucosal localization are usually small-sized, differentiated, more distinctly associated with precancer conditions.
225例确诊为胃癌的患者中,252例癌组织仅累及黏膜下层,64.5%的病例累及黏膜。7.6%的患者术后确诊为异染性早期癌。肿瘤的宏观形态各异。组织学上腺癌占主导,其高分化型在浅表癌中的发生率是浸润癌的两倍。71.8%的患者肿瘤生长伴有不同程度的上皮发育异常。重度发育异常在浅表癌中更为常见。仅局限于黏膜层的癌通常体积较小、分化良好,与癌前病变的关联更为明显。