维生素 B12。
Cobamides.
机构信息
Department of Plant & Microbial Biology, University of California Berkeley, Berkeley, CA 94720-3102, USA.
Department of Plant & Microbial Biology, University of California Berkeley, Berkeley, CA 94720-3102, USA.
出版信息
Curr Biol. 2020 Jan 20;30(2):R55-R56. doi: 10.1016/j.cub.2019.11.049.
Abstract
Vitamin B is the only known essential human micronutrient made exclusively by prokaryotes. Kennedy and Taga introduce us to the world of cobamides-those cobalt-containing compounds, like B, that appear to be the proprietary domain of our microbial partners.
摘要
维生素 B 是唯一已知的、完全由原核生物制造的人类必需微量营养素。Kennedy 和 Taga 为我们介绍了 cobamides 的世界——这些含钴的化合物，如 B 族维生素，似乎是我们微生物伙伴的专有领域。
相似文献
1
Cobamides.维生素 B12。
Curr Biol. 2020 Jan 20;30(2):R55-R56. doi: 10.1016/j.cub.2019.11.049.
2
Sharing vitamins: Cobamides unveil microbial interactions.分享维生素：钴胺素揭示微生物相互作用。
Science. 2020 Jul 3;369(6499). doi: 10.1126/science.aba0165.
3
Biosynthesis of cobamides: Methods for the detection, analysis and production of cobamides and biosynthetic intermediates.钴胺素的生物合成：钴胺素和生物合成中间产物的检测、分析和生产方法。
Methods Enzymol. 2022;668:3-23. doi: 10.1016/bs.mie.2022.01.013. Epub 2022 Feb 25.
4
Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12).对CobT同源物的底物特异性分析表明，它们普遍偏好维生素B12的较低轴向配体DMB。
Chem Biol. 2013 Oct 24;20(10):1275-85. doi: 10.1016/j.chembiol.2013.08.007. Epub 2013 Sep 19.
5
Total Synthesis, Structure, and Biological Activity of Adenosylrhodibalamin, the Non-Natural Rhodium Homologue of Coenzyme B12.腺嘌呤核苷钴胺素（辅酶 B12 的非天然铑同系物）的全合成、结构和生物活性。
Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11281-6. doi: 10.1002/anie.201603738. Epub 2016 Jun 29.
6
B vitamin acquisition by gut commensal bacteria.肠道共生细菌对维生素B的摄取
PLoS Pathog. 2020 Jan 23;16(1):e1008208. doi: 10.1371/journal.ppat.1008208. eCollection 2020 Jan.
7
[Vitamins and trace elements].[维生素与微量元素]
Ann Nutr Aliment. 1972;26(3):Suppl:B451-7.
8
Growth inhibition of Sporomusa ovata by incorporation of benzimidazole bases into cobamides.将苯并咪唑碱基掺入 cobamides 中对 Sporomusa ovata 的生长抑制作用。
J Bacteriol. 2013 May;195(9):1902-11. doi: 10.1128/JB.01282-12. Epub 2013 Feb 15.
9
Cobamide structure depends on both lower ligand availability and CobT substrate specificity.钴胺素结构既取决于较低的配体可用性，也取决于CobT底物特异性。
Chem Biol. 2013 Oct 24;20(10):1265-74. doi: 10.1016/j.chembiol.2013.08.006. Epub 2013 Sep 19.
10
Mirror "base-off" conformation of coenzyme B12 in human adenosyltransferase and its downstream target, methylmalonyl-CoA mutase.人类腺苷转移酶及其下游靶点甲基丙二酰辅酶A变位酶中辅酶B12的镜像“碱基脱离”构象
J Am Chem Soc. 2005 Jan 19;127(2):526-7. doi: 10.1021/ja044365l.
引用本文的文献
1
Nutrient smuggling: Commensal gut bacteria-derived extracellular vesicles scavenge vitamin B12 and related cobamides for microbe and host acquisition.营养物质走私：共生肠道细菌衍生的细胞外囊泡清除维生素B12及相关钴胺素以供微生物和宿主获取。
J Extracell Biol. 2022 Oct 11;1(10):e61. doi: 10.1002/jex2.61. eCollection 2022 Oct.
2
Over supplementation with vitamin B12 alters microbe-host interactions in the gut leading to accelerated Citrobacter rodentium colonization and pathogenesis in mice.过量补充维生素 B12 会改变肠道内微生物与宿主的相互作用，导致鼠柠檬酸杆菌定植和发病加速。
Microbiome. 2023 Feb 3;11(1):21. doi: 10.1186/s40168-023-01461-w.
3
Cobalamin Riboswitches Are Broadly Sensitive to Corrinoid Cofactors to Enable an Efficient Gene Regulatory Strategy.钴胺素核糖开关广泛感知类咕啉辅因子，以实现高效的基因调控策略。
mBio. 2022 Oct 26;13(5):e0112122. doi: 10.1128/mbio.01121-22. Epub 2022 Aug 22.
4
The requirement for cobalt in vitamin B: A paradigm for protein metalation.维生素 B 中钴的需求：蛋白质金属化的范例。
Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118896. doi: 10.1016/j.bbamcr.2020.118896. Epub 2020 Oct 21.
5
Antivitamins B -Some Inaugural Milestones.抗维生素 B-一些开创性的里程碑。
Chemistry. 2020 Dec 1;26(67):15438-15445. doi: 10.1002/chem.202003788. Epub 2020 Nov 3.
Zotero 插件