Sharma Rakesh K, Yadav Manavi, Gaur Rashmi, Gupta Radhika, Adholeya Alok, Gawande Manoj B
Department of Chemistry, University of Delhi, 105, Block-B, First floor, GCNC, Delhi, 110007, India.
Biotechnology and Management of Bioresources Division, The Energy and Resources Institute, Darbari Seth Block, IHC Complex, Lodhi Road, New Delhi, 110003, India.
Chempluschem. 2016 Dec;81(12):1312-1319. doi: 10.1002/cplu.201600321. Epub 2016 Sep 30.
A new, magnetic, silica-based, palladium nanocatalyst has been synthesized and employed for the first time in the direct coupling of acyl chlorides with terminal alkynes to prepare a variety of ynones. The synthesized nanocomposite is an excellent heterogeneous catalyst for copper-free, phosphine-free, C-C bond formation through the Sonogashira reaction under aerobic conditions at room temperature without the use of any additives and inert conditions. The synthesized catalyst has been comprehensively characterized by various techniques, such as XRD, SEM, TEM, energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, inductively coupled plasma, FTIR spectroscopy, vibrating sample magnetometry, and atomic absorption spectroscopy. This nanocatalyst can be magnetically recovered and reused in multiple runs without any noticeable loss in catalytic activity.
一种新型的磁性二氧化硅基钯纳米催化剂已被合成，并首次用于酰氯与末端炔烃的直接偶联反应，以制备多种炔酮。合成的纳米复合材料是一种优异的多相催化剂，可在室温有氧条件下通过Sonogashira反应实现无铜、无膦的C-C键形成，无需使用任何添加剂和惰性条件。通过XRD、SEM、TEM、能量色散X射线光谱、X射线光电子能谱、电感耦合等离子体、FTIR光谱、振动样品磁强计和原子吸收光谱等多种技术对合成的催化剂进行了全面表征。这种纳米催化剂可以通过磁性回收并多次重复使用，催化活性没有任何明显损失。
