Yano M, Otsuka T
Department of Anesthesiology, Nippon Medical School, Tokyo, Japan.
No To Shinkei. 1988 Oct;40(10):925-8.
In 9 severe head injuries whose respiration was controlled by a ventilator, continuous measurements of energy expenditure (MEE) were carried out by the ERICA Metabolic Computer. Age was ranged 19 to 69 years old (Mean 48.3 years). Glasgow Coma Scale score was 3 to 11 which were assessed the best score during 6 hours of admission. The MEE was carried out within 7 days of admission and was continued to measure more than 3 days. It measured O2 consumption and CO2 output, and calculated the indirect energy expenditure. The data were displayed and recorded every 1, 15, 60 min. The value of MEE was compared with predicted energy expenditure (PEE) which was calculated by the Harris-Benedict formula. Out of 9 patients, 6 patients were survived. High dose barbiturate therapy was performed in 7 patients to control and decrease the intracranial hypertension. Of them 3 patients died. The value of MEE in all 9 patients was variable from 77% to 212% of PEE. The value of MEE in 6 survived patients was 98.0 to 212.0% of PEE. Out of 6 patients, 4 patients who were administered high dose barbiturate showed variable data of MEE. Two patients showed about 100% of the PEE, one showed about 150%, and another one about 200%. Remaining 2 survivors who were not administered barbiturate showed about 125% of PEE, which was low value. These results were divided into two groups. In 2 patients, the value of MEE was 150% or more in spite of barbiturate therapy. In remaining 7 patients, the value of MEE was 125% or less of PEE.(ABSTRACT TRUNCATED AT 250 WORDS)
对9例使用呼吸机控制呼吸的严重颅脑损伤患者,采用ERICA代谢计算机持续测量能量消耗(MEE)。年龄在19至69岁之间(平均48.3岁)。格拉斯哥昏迷量表评分为3至11分,为入院6小时内的最佳评分。MEE在入院7天内进行,并持续测量超过3天。测量氧气消耗和二氧化碳排出量,并计算间接能量消耗。数据每1分钟、15分钟和60分钟显示并记录一次。将MEE值与通过哈里斯- Benedict公式计算的预测能量消耗(PEE)进行比较。9例患者中,6例存活。7例患者进行了大剂量巴比妥类药物治疗以控制和降低颅内压。其中3例死亡。9例患者的MEE值为PEE的77%至212%。6例存活患者的MEE值为PEE的98.0%至212.0%。6例患者中,4例接受大剂量巴比妥类药物治疗的患者MEE数据各异。2例患者的MEE约为PEE的100%,1例约为150%,另1例约为200%。其余2例未接受巴比妥类药物治疗的存活患者的MEE约为PEE的125%,此值较低。这些结果分为两组。2例患者尽管接受了巴比妥类药物治疗,MEE值仍为150%或更高。其余7例患者的MEE值为PEE的125%或更低。(摘要截断于250字)