Bilbao Nordie A, Kaulfers Anne-Marie D, Bhowmick Samar K
AACE Clin Case Rep. 2019 Apr 25;5(3):e184-e186. doi: 10.4158/ACCR-2018-0211. eCollection 2019 May-Jun.
The objective of this report is to describe the presentation, disease course, and management of subacute thyroiditis (SAT) in children. SAT is a rare cause of thyroiditis in children and can be mistaken for acute suppurative thyroiditis, which may be more common in pediatrics.
We present a 7-year-old female, who had painful thyroid enlargement, fever, and thyrotoxicosis.
Laboratory evaluation showed high white blood count, erythrocyte sedimentation rate, and free thyroxine levels. Thyroid-stimulating hormone was low. A computed tomography scan of the neck showed intrathyroidal fluid collection consistent with an abscess. She was treated with clindamycin, with no relief of fever and pain. Thyroid ultrasound showed diffuse enlargement of the thyroid lobes with hypoechoic areas, and no fluid accumulation, consistent with SAT. She was treated with intravenous ketorolac with relief of pain and fever, but these symptoms recurred when she was changed to oral ibuprofen. Her symptoms resolved with prednisolone at 1 mg/kg.
Based on the limited number of reports in the literature, SAT in children appears to be unusual and may be less common than acute bacterial thyroiditis. In pediatric practice it is important to make the distinction between SAT and acute bacterial thyroiditis.
本报告旨在描述儿童亚急性甲状腺炎(SAT)的临床表现、病程及治疗。SAT是儿童甲状腺炎的罕见病因,可能被误诊为急性化脓性甲状腺炎,后者在儿科可能更为常见。
我们报告一名7岁女性,出现甲状腺疼痛性肿大、发热及甲状腺毒症。
实验室检查显示白细胞计数、红细胞沉降率及游离甲状腺素水平升高。促甲状腺激素降低。颈部计算机断层扫描显示甲状腺内液体积聚,符合脓肿表现。给予克林霉素治疗,发热和疼痛未缓解。甲状腺超声显示甲状腺叶弥漫性肿大,有低回声区,无液体积聚,符合SAT表现。给予静脉注射酮咯酸后疼痛和发热缓解,但改为口服布洛芬后症状复发。使用泼尼松龙1mg/kg治疗后症状缓解。
基于文献中有限的报道,儿童SAT似乎不常见,可能比急性细菌性甲状腺炎更少见。在儿科临床实践中,区分SAT和急性细菌性甲状腺炎很重要。