Centauri F, Pammolli A, Simi R, Dalmasso P, Berchialla P, Borraccino A, Charrier L, Lenzi M, Vieno A, Lemma P, Cavallo F, Lazzeri G
Hospital Direction, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
J Prev Med Hyg. 2019 Dec 20;60(4):E368-E375. doi: 10.15167/2421-4248/jpmh2019.60.4.1382. eCollection 2019 Dec.
The prevalence of adolescent pain varies considerably across epidemiological studies, and little information is available on pain-related behaviours among adolescents, including medicine use. The aims of this study were: [1] to examine the prevalence of recurrent pain among 15-year-old adolescents in Italy; [2] to investigate the association between recurrent pain and medicine use among boys and girls; and [3] to evaluate the consistency of these associations across Regions.
The World Health Organization (WHO) collaborative International Health Behaviour in School-aged Children 2013/2014 study collected self-reported data on pain and medicine use from 13611 15-year-old adolescents in 21 Italian Regions. We used multi-level multivariate logistic regression, stratified by gender, to analyse the association between recurrent pain and medicine use for headache, stomachache, nervousness and difficulties in getting to sleep.
On average, across all Regions, almost 45% of adolescents reported recurrent headache, more than 30% reported recurrent backache and approximately 30% reported recurrent stomachache. Although the prevalence of both pain and medicine use was much higher among girls, the association between pain and medicine use was similarly strong in adolescents of both genders. Adolescents with recurrent pain proved more likely to use medicines also for non-corresponding pain, nervousness and difficulties in getting to sleep. The association between recurrent pain and medicine use was consistent across Regions despite large inter-regional differences in the prevalence of both phenomena.
Recurrent pain in adolescence is common nationwide. Adolescents with recurrent pain are more likely to use medicines in general. Recurrent pain and medicine use should be addressed by adolescent health policies.
青少年疼痛的患病率在不同的流行病学研究中差异很大，关于青少年与疼痛相关行为（包括药物使用）的信息很少。本研究的目的是：[1] 调查意大利15岁青少年复发性疼痛的患病率；[2] 研究男孩和女孩复发性疼痛与药物使用之间的关联；[3] 评估这些关联在各地区之间的一致性。
世界卫生组织（WHO）2013/2014年学龄儿童健康行为国际合作研究收集了来自意大利21个地区13611名15岁青少年关于疼痛和药物使用的自我报告数据。我们使用按性别分层的多水平多元逻辑回归分析复发性疼痛与头痛、胃痛、紧张和入睡困难的药物使用之间的关联。
平均而言，在所有地区，近45%的青少年报告有复发性头痛，超过30%报告有复发性背痛，约30%报告有复发性胃痛。虽然女孩中疼痛和药物使用的患病率都高得多，但疼痛与药物使用之间的关联在男女青少年中同样强烈。有复发性疼痛的青少年也更有可能使用药物来缓解非相应的疼痛、紧张和入睡困难。尽管这两种现象的患病率在各地区之间存在很大差异，但复发性疼痛与药物使用之间的关联在各地区是一致的。
青少年复发性疼痛在全国范围内很常见。一般来说，有复发性疼痛的青少年更有可能使用药物。青少年健康政策应关注复发性疼痛和药物使用问题。
