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新生大鼠肝细胞类型中的酸性脂肪酶活性。饥饿的影响。

Acid lipase activity in neonatal rat liver cell types. Effect of starvation.

作者信息

Burgaya F, Llobera M, Ramírez I

机构信息

Department de Bioquimica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain.

出版信息

Biochim Biophys Acta. 1988 Dec 16;963(3):566-9. doi: 10.1016/0005-2760(88)90328-1.

Abstract

The acid lipase activity in the liver of neonatal (1-day-old) rats was studied. It was found that (i) in whole liver, the activity was 50% lower than in adult rats; (ii) in neonatal livers, the activity was 7.7-fold higher in hepatocytes than in hemopoietic cells; (iii) neonatal hepatocytes contained about 25% of the activity detected in adult hepatocytes; (iv) all the differences disappeared when expressed per mg of protein; and (v) starvation did not affect the activity either in adult or in neonatal rat liver.

摘要

对新生(1日龄)大鼠肝脏中的酸性脂肪酶活性进行了研究。结果发现:(i)在整个肝脏中,该活性比成年大鼠低50%;(ii)在新生大鼠肝脏中,肝细胞中的活性比造血细胞高7.7倍;(iii)新生肝细胞中的活性约为成年肝细胞中检测到的活性的25%;(iv)以每毫克蛋白质计算时,所有差异均消失;(v)饥饿对成年或新生大鼠肝脏中的活性均无影响。

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