新生大鼠肝细胞类型中的酸性脂肪酶活性。饥饿的影响。

Acid lipase activity in neonatal rat liver cell types. Effect of starvation.

作者信息

Burgaya F, Llobera M, Ramírez I

机构信息

Department de Bioquimica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain.

出版信息

Biochim Biophys Acta. 1988 Dec 16;963(3):566-9. doi: 10.1016/0005-2760(88)90328-1.

DOI:10.1016/0005-2760(88)90328-1

PMID:3196752

Abstract

The acid lipase activity in the liver of neonatal (1-day-old) rats was studied. It was found that (i) in whole liver, the activity was 50% lower than in adult rats; (ii) in neonatal livers, the activity was 7.7-fold higher in hepatocytes than in hemopoietic cells; (iii) neonatal hepatocytes contained about 25% of the activity detected in adult hepatocytes; (iv) all the differences disappeared when expressed per mg of protein; and (v) starvation did not affect the activity either in adult or in neonatal rat liver.

摘要

对新生（1日龄）大鼠肝脏中的酸性脂肪酶活性进行了研究。结果发现：（i）在整个肝脏中，该活性比成年大鼠低50%；（ii）在新生大鼠肝脏中，肝细胞中的活性比造血细胞高7.7倍；（iii）新生肝细胞中的活性约为成年肝细胞中检测到的活性的25%；（iv）以每毫克蛋白质计算时，所有差异均消失；（v）饥饿对成年或新生大鼠肝脏中的活性均无影响。