Sueda Shozo, Fujimoto Kaori, Sasaki Yasuhiro, Nishimura Kazuhisa
Department of Cardiology, Ehime Niihama Prefectural Hospital, Japan.
Department of Cardiology, Ehime University, Japan.
J Cardiol Cases. 2019 Jul 8;20(4):118-121. doi: 10.1016/j.jccase.2019.06.006. eCollection 2019 Oct.
A 52-year-old man was transferred to our hospital for ventricular fibrillation. He had no chest symptoms until then. After his full recovery, the administration of acetylcholine 20 μg showed the multiple spasm (left main trunk/left anterior descending artery/right coronary artery) without any chest symptoms or ischemic electrocardiographic changes. Subcutaneous implantable cardioverter-defibrillator (S-ICD) was implanted because of no chest symptoms during his-daily-life. We performed the pharmacological spasm provocation tests under the abundant medications. Sequential spasm provocation test provoked just focal spasm at mid left anterior descending artery. We convinced that medications and S-ICD suppress the next fatal event. < LMT spasm may cause aborted SCD. Aggressive spasm provocation tests under the abundant medical therapy provoked spasm just at mid LAD artery focally in patient with VF survivor due to multiple spasm including LMT, while these medications blocked the LMT and RCA spasm. S-ICD implantation may be one of the selections in aborted SCD patients with silent LMT spasm under the abundant vasodilators in the future.>.
一名52岁男性因心室颤动被转至我院。在此之前他没有胸部症状。完全康复后,给予20μg乙酰胆碱后出现多处痉挛(左主干/左前降支动脉/右冠状动脉),但无任何胸部症状或缺血性心电图改变。由于日常生活中无胸部症状,植入了皮下植入式心律转复除颤器(S-ICD)。我们在充足的药物治疗下进行了药物性痉挛激发试验。序贯痉挛激发试验仅在左前降支动脉中段诱发了局灶性痉挛。我们确信药物和S-ICD可预防下一次致命事件。<左主干痉挛可能导致心脏性猝死未遂。在充分的药物治疗下进行积极的痉挛激发试验,在因包括左主干在内的多处痉挛而发生心室颤动幸存者中,仅在左前降支动脉中段局灶性诱发了痉挛,而这些药物可阻断左主干和右冠状动脉痉挛。未来,S-ICD植入可能是在充足血管扩张剂治疗下无症状左主干痉挛的心脏性猝死未遂患者的选择之一。>