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一名儿科患者的原发性T细胞起源胸膜淋巴瘤,重点关注影像学表现——病例报告及文献复习

Primary pleural lymphoma of T cell origin in a paediatric patient with a focus on radiological findings - a case report and review of literature.

作者信息

Jahanshahi Amirreza, Hiradfar Amirataollah, Zarrintan Armin, Mirza-Aghazadeh-Attari Mohammad

机构信息

Department of Radiology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Pol J Radiol. 2019 Sep 16;84:e353-e359. doi: 10.5114/pjr.2019.88773. eCollection 2019.

Abstract

PURPOSE

Pleural lymphoma is a medical condition characterised by shortness of breath and obscure chest pain, which may be a diagnostic challenge, especially when it occurs in children. Plain chest X-rays and computed tomography (CT) scan are the main imaging techniques and are the initial diagnostic methods utilised.

CASE REPORT

A four-year-old boy was admitted to the emergency ward with pain in the right thoracoabdominal region, which had persisted for two months. Physical examination revealed reduced respiratory sounds in the right chest, but with no other significant findings. The patient underwent chest X-ray and CT scan, which showed right sided pleural thickening coupled with a massive pleural effusion. The patient underwent pleural biopsy, and a diagnosis of T-cell primary pleural lymphoma was made. The patient underwent treatment with BFM-NHL and was followed for three years, during which the patient remained disease free.

CONCLUSIONS

Pleural lymphoma is a rare diagnosis especially in children and could have overlapping clinical manifestations with more common conditions. Imaging techniques are the main route of clinical work-up towards final diagnosis. Here, we present a rare paediatric patient with no significant past medical history, who underwent imaging and was diagnosed with T-cell primary pleural lymphoma, a very rare subtype of primary pleural lymphoma.

摘要

目的

胸膜淋巴瘤是一种以呼吸急促和不明原因胸痛为特征的病症,可能是一个诊断难题,尤其是在儿童中出现时。胸部X线平片和计算机断层扫描(CT)是主要的成像技术,也是最初使用的诊断方法。

病例报告

一名4岁男孩因右胸腹部疼痛持续两个月入住急诊病房。体格检查发现右胸呼吸音减弱,但无其他明显异常。患者接受了胸部X线和CT扫描,结果显示右侧胸膜增厚并伴有大量胸腔积液。患者接受了胸膜活检,诊断为T细胞原发性胸膜淋巴瘤。患者接受了BFM-NHL方案治疗,并随访了三年,在此期间患者无疾病复发。

结论

胸膜淋巴瘤是一种罕见的诊断,尤其是在儿童中,其临床表现可能与更常见的疾病重叠。成像技术是最终诊断临床检查的主要途径。在此,我们报告一例罕见的儿科患者,其既往无重大病史,经影像学检查诊断为T细胞原发性胸膜淋巴瘤,这是原发性胸膜淋巴瘤中一种非常罕见的亚型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aab/6964326/02333e39b488/PJR-84-38046-g001.jpg

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