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小儿T细胞淋巴母细胞淋巴瘤的广泛胸膜受累

Extensive Pleural Involvement in Pediatric T-Cell Lymphoblastic Lymphoma.

作者信息

Jain Bela, Saini Vivek Kumar, Mishra Ayush, Ora Manish, Gambhir Sanjay

机构信息

Department of Nuclear Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Indian J Nucl Med. 2022 Apr-Jun;37(2):175-177. doi: 10.4103/ijnm.ijnm_190_21. Epub 2022 Jul 8.

DOI:10.4103/ijnm.ijnm_190_21
PMID:35982822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9380812/
Abstract

Lymphoblastic lymphoma (LBL) is the common non-Hodgkin lymphoma in childhood and adolescence. T-cell LBL (T-LBL) usually manifests with an anterior mediastinal mass and disseminated disease. We present a 12-year-old girl with progressive neck swelling and dyspnea for 1 year. Fluorodeoxyglucose positron-emission tomography/computed tomography done for pretreatment staging unveiled hypermetabolic lymph nodes on both sides of the diaphragm with splenic and bone marrow involvement. Apart from these, there was the extensive involvement of the left pleura. Biopsy and immunohistochemistry revealed T-LBL. The extensive secondary pleural involvement in pediatric T-LBL is rarely seen and needs to be reported.

摘要

淋巴母细胞淋巴瘤(LBL)是儿童和青少年常见的非霍奇金淋巴瘤。T细胞LBL(T-LBL)通常表现为前纵隔肿块和播散性疾病。我们报告一名12岁女孩,颈部进行性肿胀和呼吸困难1年。为进行预处理分期而进行的氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描显示,双侧膈肌淋巴结代谢增高,脾脏和骨髓受累。除此之外,左侧胸膜广泛受累。活检及免疫组化显示为T-LBL。小儿T-LBL广泛的继发性胸膜受累很少见,需要报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/9380812/2685a2ef70fc/IJNM-37-175-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/9380812/2685a2ef70fc/IJNM-37-175-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/9380812/2685a2ef70fc/IJNM-37-175-g001.jpg

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本文引用的文献

1
Primary pleural lymphoma of T cell origin in a paediatric patient with a focus on radiological findings - a case report and review of literature.一名儿科患者的原发性T细胞起源胸膜淋巴瘤,重点关注影像学表现——病例报告及文献复习
Pol J Radiol. 2019 Sep 16;84:e353-e359. doi: 10.5114/pjr.2019.88773. eCollection 2019.
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Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities.儿童和青少年淋巴母细胞淋巴瘤:当前挑战和未来机遇的综述。
Br J Haematol. 2019 Jun;185(6):1158-1170. doi: 10.1111/bjh.15793. Epub 2019 Feb 27.
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Fluorine-18 fluorodeoxyglucose positron emission tomography imaging of T-lymphoblastic lymphoma patients.
T淋巴母细胞淋巴瘤患者的氟-18氟脱氧葡萄糖正电子发射断层扫描成像
Oncol Lett. 2016 Aug;12(2):1620-1622. doi: 10.3892/ol.2016.4806. Epub 2016 Jun 29.
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Precursor T-cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report.前体T细胞淋巴母细胞淋巴瘤广泛累及纵隔、胸膜和心包:一例报告。
Mol Clin Oncol. 2014 Nov;2(6):945-948. doi: 10.3892/mco.2014.347. Epub 2014 Jul 11.
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FDG PET/CT of extranodal involvement in non-Hodgkin lymphoma and Hodgkin disease.FDG PET/CT 在外周非霍奇金淋巴瘤和霍奇金病中的应用。
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Arch Pathol Lab Med. 2006 Oct;130(10):1497-502. doi: 10.5858/2006-130-1497-LITPAC.
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The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence.年龄和性别对儿童及青少年非霍奇金淋巴瘤生物学特性、临床特征及治疗结果的影响。
Br J Haematol. 2005 Oct;131(1):39-49. doi: 10.1111/j.1365-2141.2005.05735.x.
9
Pleural effusions in hematologic malignancies.血液系统恶性肿瘤中的胸腔积液
Chest. 2004 Apr;125(4):1546-55. doi: 10.1378/chest.125.4.1546.