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肺毛霉病:一例罕见感染伴潜在诊断问题的病例报告

Pulmonary Mucormycosis: A Case Report of a Rare Infection with Potential Diagnostic Problems.

作者信息

Mekki Salwa O, Hassan Amal A, Falemban Afnan, Alkotani Nashwa, Alsharif Salem M, Haron Ahmed, Felemban Basim, Iqbal Mohammad S, Tabassum Aisha

机构信息

Pathology Department, Alnoor Specialist Hospital, Makkah, Saudi Arabia.

Faculty of Medicine, Al Neelain University, Khartoum, Sudan.

出版信息

Case Rep Pathol. 2020 Jan 6;2020:5845394. doi: 10.1155/2020/5845394. eCollection 2020.

Abstract

Pulmonary mucormycosis is a relatively rare pulmonary fungal disease, which is difficult to diagnose early and lacks effective treatment. It is seen in patients with hematological malignancies, diabetes mellitus, and immunocompromised states. The diagnosis depends primarily on the detection of fungi in lung tissue. Here, we present a case of a 52-year-old male who has type 2 diabetes mellitus and a past history of treated pulmonary tuberculosis. Clinical diagnosis is difficult in pulmonary mucormycosis, and early diagnosis is needed for this life-threatening infection. Histopathological examination of a resected cavity confirmed the diagnosis of pulmonary mucormycosis. This report highlights the difficulty of diagnosis and the importance of histological examination in detecting mucormycosis which will help for early management.

摘要

肺毛霉病是一种相对罕见的肺部真菌病,早期难以诊断且缺乏有效治疗方法。多见于血液系统恶性肿瘤、糖尿病及免疫功能低下的患者。诊断主要依靠在肺组织中检测到真菌。在此,我们报告一例52岁男性患者,他患有2型糖尿病且有肺结核治疗史。肺毛霉病的临床诊断困难,对于这种危及生命的感染需要早期诊断。对切除的空洞进行组织病理学检查确诊为肺毛霉病。本报告强调了诊断的困难以及组织学检查在检测毛霉病中的重要性,这将有助于早期治疗。

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