Salvesen R, Sand T, Sjaastad O
Department of Neurology, Regionsykehuset, Trondheim University Hospital, Norway.
Cephalalgia. 1988 Sep;8(3):211-8. doi: 10.1046/j.1468-2982.1988.0803211.x.
Twenty-nine patients with cluster headache have been examined with the pupillometer and the evaporimeter. Pupils were dilated by sympathicomimetic drugs instilled into the conjunctival sacs, and responses of the two sides were compared. Forehead sweating was stimulated by body heating and by pilocarpine injection, and sweat evaporation on the two sides was compared. Most patients demonstrated the known patterns of hyposecretion on heating, of pilocarpine supersensitivity, and of deficient pupillary dilatation on OH-amphetamine stimulation on the symptomatic side and a supersensitivity of this pupil to phenylephrine. There were deviations from the rule for all methods of testing. Sixteen patients demonstrated a typical supersensitivity response of the pupil and of the sweat glands on the symptomatic side. Six patients had no such response, and seven patients had a discrepancy between the pupillary and the sweat gland response to stimulation, supersensitivity being present in one system only. There was a high degree of concordance between the results of the various methods of examination.
对29例丛集性头痛患者使用瞳孔计和蒸发计进行了检查。通过将拟交感神经药物滴入结膜囊使瞳孔扩张，并比较两侧的反应。通过身体加热和注射毛果芸香碱刺激前额出汗，并比较两侧的汗液蒸发情况。大多数患者在症状侧表现出已知的受热时分泌减少、对毛果芸香碱超敏以及在去氧肾上腺素刺激下瞳孔扩张不足的模式，且该侧瞳孔对去氧肾上腺素超敏。所有检测方法均存在偏离规则的情况。16例患者在症状侧表现出典型的瞳孔和汗腺超敏反应。6例患者没有这种反应，7例患者在瞳孔和汗腺对刺激的反应之间存在差异，仅在一个系统中存在超敏反应。各种检查方法的结果之间存在高度一致性。
