Drummond P D
Department of Neurology, Prince Henry Hospital, Sydney, N.S.W., Australia.
Cephalalgia. 1988 Sep;8(3):181-6. doi: 10.1046/j.1468-2982.1988.0803181.x.
Ocular sympathetic function was studied in 13 cluster headache patients during and between attacks and several weeks or months after attacks had subsided. The pupillary response to tyramine eyedrops and facial sweating and flushing in response to body heating and to the taste of chilies were also investigated during remission. Pupillary dilatation lag on the symptomatic side persisted between bouts and correlated significantly with loss of thermoregulatory sweating in the lower part of the forehead. In six patients in remission, pupillary dilatation in response to tyramine eyedrops was impaired on the symptomatic side, whereas five patients showed no sign of ocular sympathetic deficit. These findings indicate that incomplete sympathetic deficit persisted on the symptomatic side in a subgroup of cluster headache patients during remission. In most of this subgroup the pattern of sympathetic deficit was consistent with impaired function of postganglionic cervical sympathetic fibres.
在13例丛集性头痛患者发作期间、发作间歇期以及发作消退数周或数月后，对其眼部交感神经功能进行了研究。在缓解期，还研究了对酪氨酸滴眼剂的瞳孔反应以及对身体加热和辣椒味道的面部出汗和潮红情况。症状侧的瞳孔扩张滞后在发作间期持续存在，并且与前额下部体温调节性出汗的丧失显著相关。在6例缓解期患者中，症状侧对酪氨酸滴眼剂的瞳孔扩张受损，而5例患者未显示眼部交感神经功能缺陷的迹象。这些发现表明，在缓解期，丛集性头痛患者的一个亚组中，症状侧存在不完全的交感神经功能缺陷。在该亚组的大多数患者中，交感神经功能缺陷的模式与节后颈交感神经纤维功能受损一致。
