大麻哈鱼（Oncorhynchus keta）阿黑皮素原信使核糖核酸中γ-促黑素细胞激素序列的缺失。
Absence of a gamma-melanocyte-stimulating hormone sequence in proopiomelanocortin mRNA of chum salmon Oncorhynchus keta.
作者信息
Kitahara N, Nishizawa T, Iida K, Okazaki H, Andoh T, Soma G I
机构信息
Biotechnology Research Center, Teikyo University, Kanagawa, Japan.
出版信息
Comp Biochem Physiol B. 1988;91(2):365-70. doi: 10.1016/0305-0491(88)90155-1.
PMID:3197404
Abstract
- Complete nucleotide sequence of one of the salmon proopiomelanocortin mRNAs (POMC mRNAs) was determined. 2. The region corresponding to gamma-melanocyte-stimulating hormone (gamma-MSH) was lacking in salmon POMC mRNA, although overall organization of the multi-hormone structure was exactly the same as that of mammalian POMC mRNAs. 3. The possible evolutional history of POMC mRNA in mammalian species may be revealed from the finding of this characteristic that salmon POMC mRNA lacks the region corresponding to gamma-MSH.
摘要
- 测定了鲑鱼阿黑皮素原mRNA（POMC mRNA）之一的完整核苷酸序列。2. 鲑鱼POMC mRNA中缺少与γ-黑素细胞刺激素（γ-MSH）相对应的区域，尽管多激素结构的总体组织与哺乳动物POMC mRNA完全相同。3. 从鲑鱼POMC mRNA缺乏与γ-MSH相对应区域这一特征的发现中，可能揭示哺乳动物物种中POMC mRNA的可能进化史。
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