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Impact of a Direct-Fed Microbial on Growth Performance, Intestinal Barrier Integrity, Necrotic Enteritis Lesions, and Ileal Microbiota in Broiler Chickens Using a Laboratory Challenge Model.使用实验室攻毒模型研究直接投喂微生物对肉鸡生长性能、肠道屏障完整性、坏死性肠炎病变及回肠微生物群的影响
Front Vet Sci. 2019 Apr 24;6:108. doi: 10.3389/fvets.2019.00108. eCollection 2019.
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VFDB 2019: a comparative pathogenomic platform with an interactive web interface.VFDB 2019:一个具有交互式网络界面的比较病原体基因组学平台。
Nucleic Acids Res. 2019 Jan 8;47(D1):D687-D692. doi: 10.1093/nar/gky1080.
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Enterotoxic Clostridia: Enteric Diseases.肠毒素梭菌:肠道疾病。
Microbiol Spectr. 2018 Sep;6(5). doi: 10.1128/microbiolspec.GPP3-0003-2017.
4
Evaluation of the Epithelial Barrier Function and Ileal Microbiome in an Established Necrotic Enteritis Challenge Model in Broiler Chickens.在已建立的肉鸡坏死性肠炎攻毒模型中评估上皮屏障功能和回肠微生物群
Front Vet Sci. 2018 Aug 21;5:199. doi: 10.3389/fvets.2018.00199. eCollection 2018.
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Expansion of the Clostridium perfringens toxin-based typing scheme.基于产气荚膜梭菌毒素的分型方案的扩展。
Anaerobe. 2018 Oct;53:5-10. doi: 10.1016/j.anaerobe.2018.04.011. Epub 2018 Apr 20.
6
Conjugation-Mediated Horizontal Gene Transfer of Clostridium perfringens Plasmids in the Chicken Gastrointestinal Tract Results in the Formation of New Virulent Strains.梭状芽孢杆菌质粒在鸡胃肠道中的连接介导水平基因转移导致新的毒力株的形成。
Appl Environ Microbiol. 2017 Dec 1;83(24). doi: 10.1128/AEM.01814-17. Print 2017 Dec 15.
7
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database.CARD 2017:全面抗生素抗性数据库的扩展及以模型为中心的管理
Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. doi: 10.1093/nar/gkw1004. Epub 2016 Oct 26.
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NCBI prokaryotic genome annotation pipeline.美国国立生物技术信息中心原核生物基因组注释管道
Nucleic Acids Res. 2016 Aug 19;44(14):6614-24. doi: 10.1093/nar/gkw569. Epub 2016 Jun 24.
9
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QUAST: quality assessment tool for genome assemblies.QUAST:基因组组装质量评估工具。
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产气荚膜梭菌TAMU菌株的基因组序列草图,该菌株可引起肉鸡坏死性肠炎。

Draft Genome Sequence of Clostridium perfringens Strain TAMU, Which Causes Necrotic Enteritis in Broiler Chickens.

作者信息

Ausland Catherine, Al-Ogaili Adil Sabr, Latorre Juan D, Tellez-Isaias Guillermo, Hargis Billy M, Kwon Young Min, Arreguin-Nava Margarita A, Singh Pallavi

机构信息

Department of Biological Sciences, Northern Illinois University, DeKalb, Illinois, USA.

Department of Poultry Science, University of Arkansas, Fayetteville, Arkansas, USA.

出版信息

Microbiol Resour Announc. 2020 Jan 23;9(4):e01357-19. doi: 10.1128/MRA.01357-19.

DOI:10.1128/MRA.01357-19
PMID:31974152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6979301/
Abstract

causes severe gastrointestinal diseases, which include necrotic enteritis (NE) in chickens, a deadly disease worldwide. We report here the draft genome sequence of strain TAMU, which was used in developing an NE chicken challenge model. This TAMU genome sequence will aid in advancing potential intervention strategies to reduce NE pathogenesis.

摘要

引发严重的胃肠道疾病,其中包括鸡的坏死性肠炎(NE),这是一种在全球范围内具有致命性的疾病。我们在此报告TAMU菌株的基因组序列草图,该菌株被用于开发一种NE鸡攻毒模型。这个TAMU基因组序列将有助于推进潜在的干预策略,以降低NE的发病机制。