Diurnal effects on debrisoquine hydroxylation phenotyping.
作者信息
Lee E J
机构信息
Department of Pharmacology, National University of Singapore.
出版信息
Eur J Clin Pharmacol. 1988;35(4):441-2. doi: 10.1007/BF00561381.
PMID:3197754
Abstract
A study was performed to show whether debrisoquine phenotyping could be performed as an overnight procedure. Phenotyping of 33 normal volunteers was carried out during the day and night. A good correlation was observed between the day- and night-time metabolic ratios, although wide variation was observed in 3 subjects.
摘要
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