Mitichashvili R S, Kochlashvili T I, Mirtskhulava E G, Savina M A, Ermolaev V I
Genetika. 1988 Sep;24(9):1665-70.
A series of intraspecific immunizations of pigs by whole blood serum in complete Freund's adjuvant was performed. Four allo-antisera to different serum allotypes were obtained. These allotypes were assigned to A1, B1, C1 and D1. The results of identification show that the allotype A1 is probably a marker of immunoglobulin G. The allotypes B1, C1 and D1 were established to belong to different alpha-globulins, D1 being a marker of lipoprotein. Two geographically isolated populations of white large breed were tested. Two allotype combinations were found to be independent of one another and of sex. Significant differences in allotype frequency between two populations were only established for the G1 (F = 0.142 and 0.334; P less than 0.01). In both populations allotype B1 has the frequency 1.0, the frequencies of allotype A1 being 0.734 and 0.747. Most rare is the allotype D1 (F = 0.078 and 0.082).
采用完全弗氏佐剂中的全血血清对猪进行了一系列种内免疫接种。获得了针对不同血清同种异型的四种同种抗血清。这些同种异型被指定为A1、B1、C1和D1。鉴定结果表明，同种异型A1可能是免疫球蛋白G的一个标记。已确定同种异型B1、C1和D1属于不同的α-球蛋白，D1是脂蛋白的一个标记。对两个地理隔离的大白猪群体进行了检测。发现两种同种异型组合彼此独立且与性别无关。仅在G1方面确定了两个群体之间同种异型频率的显著差异（F = 0.142和0.334；P小于0.01）。在两个群体中，同种异型B1的频率均为1.0，同种异型A1的频率分别为0.734和0.747。最罕见的是同种异型D1（F = 0.078和0.082）。
