Medizinische Klinik und Poliklinik IV, Schwerpunkt Akutgeriatrie, Klinikum der Universität München (LMU), Munich, Germany.
Medizinische Klinik und Poliklinik IV, Schwerpunkt Akutgeriatrie, Klinikum der Universität München (LMU), Munich, Germany.
J Am Med Dir Assoc. 2020 Jun;21(6):747-751.e1. doi: 10.1016/j.jamda.2019.12.011. Epub 2020 Jan 21.
Translation, adaptation, and validation of the German version of the SARC-F for community-dwelling older adults in Germany.
Cross-sectional.
117 community-dwelling outpatients with a mean age of 79.1 ± 5.2 years were included in the study; 94 (80.4%) of them were female. Sixty-three (53.8%) had a positive SARC-F score of ≥4 points. According to the definition of sarcopenia from the European Working Group on Sarcopenia in Older People (EWGSOP2), 8 patients (6.8%) were identified as sarcopenic and 57 (48.7%) as probable sarcopenic.
According to EWGSOP2, probable sarcopenia was defined for patients with reduced hand grip strength (women: <16.0 kg; men: <27.0 kg) and/or impaired chair-rise time (both genders: >15 seconds). Patients with additional low skeletal muscle index were classified as sarcopenic (women: <5.5 kg/m; men: <7.0 kg/m). Translation and cultural adaption was composed of 7 different steps that were in general based on the guidelines put forward by the World Health Organization. Validation include test-retest and the inter-rater reliability (intraclass correlation coefficient) as well as internal consistency (Cronbach alpha). Furthermore, sensitivity, specificity, positive predictive value, and negative predictive value of the SARC-F were calculated. Receiver-operating characteristic analysis was performed to calculate the area under the curve.
The translated and culturally adapted version of the SARC-F for the German language has shown excellent inter-rater reliability and good test-retest reliability. The internal consistency is acceptable. Sensitivity (63%) and specificity (47%) for sarcopenia is low. For detecting patients with probable sarcopenia, the SARC-F in the German version has shown 75% sensitivity and 67% specificity.
Because of a low sensitivity for detecting sarcopenia but an acceptable sensitivity for identifying probable sarcopenia, the German version of the SARC-F is a suitable tool for case finding of probable sarcopenia.
将德国版 SARC-F 翻译、改编并验证为适用于德国社区居住的老年人。
横断面研究。
纳入了 117 名平均年龄为 79.1±5.2 岁的社区居住的门诊患者；其中 94 名（80.4%）为女性。63 名（53.8%）的 SARC-F 评分≥4 分呈阳性。根据欧洲老年人肌少症工作组（EWGSOP2）的肌少症定义，8 名患者（6.8%）被确定为肌少症，57 名患者（48.7%）为疑似肌少症。
根据 EWGSOP2，对于握力降低的患者（女性：<16.0kg；男性：<27.0kg）和/或起坐时间延长的患者（两性：>15 秒），定义为疑似肌少症。对于存在额外低骨骼肌指数的患者，将其分类为肌少症（女性：<5.5kg/m；男性：<7.0kg/m）。翻译和文化适应由 7 个不同步骤组成，总体上基于世界卫生组织提出的指南。验证包括测试-重测和评分者间可靠性（组内相关系数）以及内部一致性（Cronbach α）。此外，计算了 SARC-F 的敏感性、特异性、阳性预测值和阴性预测值。进行了接收者操作特征分析以计算曲线下面积。
翻译和文化适应后的德国版 SARC-F 显示出极好的评分者间可靠性和良好的测试-重测可靠性。内部一致性是可以接受的。肌少症的敏感性（63%）和特异性（47%）较低。对于检测疑似肌少症患者，德国版 SARC-F 的敏感性为 75%，特异性为 67%。
由于检测肌少症的敏感性较低，但识别疑似肌少症的敏感性可接受，因此德国版 SARC-F 是一种适合用于疑似肌少症病例发现的工具。
