University Cardiology, AOU Città della Salute e della Scienza di Torino, Torino, Piemonte, Italy
Department of Medical Sciences, University of Turin, Torino, Piemonte, Italy.
Heart. 2020 Apr;106(8):569-574. doi: 10.1136/heartjnl-2019-315852. Epub 2020 Jan 24.
Neoplastic pericardial effusion is a common and serious manifestation of advanced malignancies. Lung and breast carcinoma, haematological malignancies, and gastrointestinal cancer are the most common types of cancer involving the pericardium. Pericardial involvement in neoplasia may arise from several different pathophysiological mechanisms and may be manifested by pericardial effusion with or without tamponade, effusive-constrictive pericarditis and constrictive pericarditis. Management of these patients is a complex multidisciplinary problem, affected by clinical status and prognosis of patients.
肿瘤性心包积液是晚期恶性肿瘤的常见且严重的表现。肺癌和乳腺癌、血液系统恶性肿瘤和胃肠道癌是最常见的累及心包的癌症类型。肿瘤在心包的累及可能源于几种不同的病理生理机制,并可能表现为有心包填塞或无心包填塞的心包积液、渗出性缩窄性心包炎和缩窄性心包炎。这些患者的管理是一个复杂的多学科问题,受患者的临床状况和预后影响。