Tokyo University of Agriculture and Technology, Department of Veterinary Surgery, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-0052, Japan.
Teikyo University of Science, Department of Animal Science, 2-2-1, Senjyusakuragi, Adachi-ku, Tokyo, 120-0045, Japan.
Sci Rep. 2020 Jan 24;10(1):1106. doi: 10.1038/s41598-019-57180-6.
Vorticity is a novel index that reflects diastolic function of left ventricle. The size of the ventricle can influence the ventricular diastolic blood flow. We evaluated effect of ventricular size on diastolic function and diastolic intracardiac blood flow using a particular species of dogs, which has a wide range of body size. Vector flow mapping was used for evaluation of intracardiac blood flow, and intraventricular pressure gradient (IVPG) was used for evaluation of diastolic function. 58 dogs weighing 1.3-42.3 kg were included in this study. Vorticity was found to be inversely proportional to the length of the ventricular chamber. Intraventricular pressure difference was positively correlated with the length of the left ventricle, whereas IVPG was not. This study showed that the vorticity is influenced by the size of the left ventricle independently of other factors. To evaluate the hemodynamic state of each individual appropriately by using vorticity and IVPD, ventricular size should be taken into account especially in the field of veterinary medicine and human pediatric and adolescent cardiology.
涡度是反映左心室舒张功能的新指标。心室的大小会影响心室舒张期的血流。我们使用一种体型范围广泛的特殊犬种来评估心室大小对舒张功能和舒张期心内血流的影响。向量血流图用于评估心内血流，心室间压力梯度（IVPG）用于评估舒张功能。本研究纳入了 58 只体重为 1.3-42.3kg 的犬。涡度与心室腔的长度成反比。左心室长度与室内压差呈正相关，而 IVPG 则无相关性。本研究表明，涡度受左心室大小的影响，与其他因素无关。为了通过使用涡度和 IVPD 来评估每个个体的血流动力学状态，特别是在兽医和儿科青少年心脏病学领域，应该考虑心室大小。
