University of Groningen, University Medical Center Groningen, University Center of Psychiatry, Rob Giel Onderzoekcentrum, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Department of Neuroscience, Cognitive Neuroscience Center, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands.
Eur Arch Psychiatry Clin Neurosci. 2021 Mar;271(2):355-366. doi: 10.1007/s00406-020-01097-z. Epub 2020 Jan 24.
Individuals with a psychotic disorder are at an increased risk of becoming the victim of a crime. A body-oriented resilience therapy (BEATVIC) aimed at preventing victimization by addressing putatively underlying factors was developed. One of these factors is social cognition, particularly facial affect processing. The current study investigated neural effects of BEATVIC on facial affect processing using two face processing tasks. Participants were randomized to either BEATVIC or a 'Befriending' control group. Twenty-seven patients completed an Emotional Faces task and the Wall of Faces task during fMRI, pre- and post-intervention. General linear model analyses yielded no differences between groups over time. Independent component analyses revealed increased activation of the salience network to angry and fearful faces in BEATVIC compared to Befriending. Increased activation of the salience network may suggest an increased alertness for potentially dangerous faces.
患有精神病的个体成为犯罪受害者的风险增加。为了预防犯罪，我们开发了一种针对潜在基础因素的以身体为中心的韧性治疗方法（BEATVIC）。这些因素之一是社会认知，特别是面部情感处理。本研究使用两种面部处理任务，调查了 BEATVIC 对面部情感处理的神经影响。参与者被随机分配到 BEATVIC 或“交友”对照组。27 名患者在 fMRI 检查前和治疗后完成了情绪面孔任务和面孔墙任务。一般线性模型分析显示，两组之间在时间上没有差异。独立成分分析显示，与交友组相比，BEATVIC 组对愤怒和恐惧面孔的显着网络激活增加。显着网络的激活增加可能表明对潜在危险面孔的警觉性提高。
