Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Department of Prosthetic Dentistry, Faculty of Medicine, Medical Center - University of Freiburg, Center for Dental Medicine, University of Freiburg, Freiburg, Germany.
Clin Oral Implants Res. 2020 May;31(5):452-462. doi: 10.1111/clr.13581. Epub 2020 Feb 5.
To evaluate the clinical and radiological outcomes of one-piece zirconia implants restored with single crowns (SCs) or fixed dental prostheses (FDPs) over an observation period of 5 years in function.
In a prospective cohort investigation with two investigational centers, one-piece zirconia implants were placed in anterior and posterior sites. After a healing period of at least 2 months in the mandible and 4 months in the maxilla with immediate provisional reconstructions, the final all-ceramic SCs or three-unit FDPs were cemented. Patients were followed for 5 years. Clinical parameters and radiological measurements of the implants and the neighboring teeth were assessed. For the statistical analysis, linear mixed models were applied.
A total of 71 implants were placed in 60 patients. Sixty-three implants in 53 patients could be evaluated at the 5-year follow-up. Six patients with a total of seven implants were counted as dropouts. One implant did not achieve adequate osseointegration and had to be removed 5 weeks after implantation. The 5-year survival rate was calculated as 98.4% (95% CI 91.6, 99.9). The mean overall marginal bone loss from implant placement to the 5-year follow-up was 0.7 ± 0.6 mm. After an initial mean marginal loss before loading the implants (0.7 mm), no further statistically significant change in marginal bone level (p = .458) could be observed.
The investigated one-piece zirconia implant showed a high survival rate, very stable marginal bone, and mucosal margin levels after 5 years in function. Therefore, it can be considered safe and reliable for the reconstruction of implant-supported SCs or FDPs over a mid-term period.
评估一体式氧化锆种植体在功能观察期 5 年内，通过单冠（SCs）或固定义齿（FDPs）修复的临床和影像学结果。
在一项具有两个研究中心的前瞻性队列研究中，将一体式氧化锆种植体放置在前牙和后牙部位。在下颌至少 2 个月、上颌至少 4 个月的愈合期后，立即进行临时重建，然后粘结最终的全陶瓷 SCs 或三单位 FDPs。患者随访 5 年。评估种植体和相邻牙齿的临床参数和影像学测量值。统计分析采用线性混合模型。
共放置了 71 个种植体，涉及 60 名患者。53 名患者中的 63 个种植体可在 5 年随访时进行评估。6 名患者共 7 个种植体被计为脱落病例。1 个种植体未达到足够的骨整合，植入后 5 周需要取出。5 年生存率计算为 98.4%（95%CI 91.6，99.9）。从种植体放置到 5 年随访的平均总边缘骨损失为 0.7±0.6mm。在植入前种植体初始平均边缘损失（0.7mm）后，边缘骨水平没有进一步的统计学显著变化（p=0.458）。
经过 5 年的功能使用，研究中所涉及的一体式氧化锆种植体具有较高的存活率、非常稳定的边缘骨和黏膜边缘水平。因此，它可以被认为是一种安全可靠的方法，适用于中短期种植体支持的 SCs 或 FDPs 的修复。
