Drummond G B, Davie I T, Scott D B
Br J Anaesth. 1977 Feb;49(2):151-4. doi: 10.1093/bja/49.2.151.
Naloxone was used to antagonize the respiratory depression caused by the administration of fentanyl 0.05 mg to patients anaesthetized with 0.5% halothane in 70% nitrous oxide in oxygen. Four groups of at least 10 patients each were studied. Doses of 0.1, 0.2 and 0.4 mg of naloxone were given, and an effect proportional to the logarithm of the dose was demonstrated.
纳洛酮用于拮抗在70%氧化亚氮和氧气混合气体中用0.5%氟烷麻醉的患者静脉注射0.05毫克芬太尼后引起的呼吸抑制。每组至少10例患者，共四组。分别给予0.1毫克、0.2毫克和0.4毫克的纳洛酮，结果显示其效应与剂量的对数成正比。
