Abou-madi M N, Chin S P, Yaboub J M, Keszler H
Anesth Analg (Paris). 1976 Sep-Oct;33(5):757-62.
Two comparable groups of ten patients were studied. After nitrous oxide-oxygen fentanyl-pancuronium anesthesia, half the patients were reversed with a titrated dose of naloxone. Even in titrated doses naloxone rapidly abolished residual post-operative fentanyl analgesia in 80 p. 100 of the patients. In the control group none of the patients complained of pain for an average of six to eight hours. Blood gases in the recovery room were practically the same in reversed and non-reversed patients and were satisfactory.
对两组各十名患者进行了研究。在氧化亚氮 - 氧气 - 芬太尼 - 潘库溴铵麻醉后，一半患者用滴定剂量的纳洛酮进行逆转。即使是滴定剂量的纳洛酮，也能迅速消除80%的患者术后残留的芬太尼镇痛作用。在对照组中，平均六至八小时内没有患者抱怨疼痛。逆转组和未逆转组患者在恢复室的血气情况基本相同，且都令人满意。
