Svintsitskyy Anatoliy, Solovyova Galyna, Maliarov Sergiy, Alianova Tetiana
Bogomolets National Medical University, Kyiv, Ukraine
“Oberig” Clinic, Kyiv, Ukraine
Wiad Lek. 2019 Oct 31;72(10):1872-1877.
Among all causes of epigastric pain or burning, early satiety, bothersome fullness, the most common one is functional dyspepsia (FD). Analysis of psychological peculiarities of patients with FD becomes one of the key problems. The aim: To compare the level of anxiety, depression, and social functioning of patients with postprandial distress syndrome (PDS), patients with epigastric pain syndrome (EBS), and healthy volunteers.
This cross-sectional study was conducted in adult patients with FD (58 patients with PDS and 37 patients with EPS) and healthy volunteers (30 persons). Patients’ social functioning was assessed with the 36-Item Short Form Health Survey (SF-36). Anxiety and depression levels were measured with the Hospital Anxiety and Depression Scale (HADS).
Patients with PDS showed significantly lower rates of physical functioning (p=0.0002), role physical (p=0.003), bodily pain (p=0.0001), general health (p=0.0001), vitality (p=0.0001), and social functioning (p=0.0003), in comparison with healthy volunteers. This group also showed significantly lower rates of general health (p=0.041), and social functioning (p=0.048), as compared to patients with EPS. FD led to an increase in anxiety levels regardless of the type of disease as compared with healthy volunteers (p=0.024). Patients with PDS had elevated depression levels compared to patients with EPS (p=0.023) and healthy volunteers (p=0.001).
Each type of FD has a certain impact on the social functioning, anxiety and depression levels. Patients with PDS manifested significant differences in the psychological state as compared to patients with EPS, and healthy volunteers.
在引起上腹部疼痛或烧灼感、早饱、令人烦恼的饱腹感的所有原因中，最常见的是功能性消化不良（FD）。分析FD患者的心理特点成为关键问题之一。目的：比较餐后不适综合征（PDS）患者、上腹部疼痛综合征（EPS）患者和健康志愿者的焦虑、抑郁水平及社会功能。
本横断面研究纳入成年FD患者（58例PDS患者和37例EPS患者）及健康志愿者（30人）。采用36项简明健康状况调查量表（SF-36）评估患者的社会功能。采用医院焦虑抑郁量表（HADS）测量焦虑和抑郁水平。
与健康志愿者相比，PDS患者在生理功能（p = 0.0002）、生理角色（p = 0.003）、身体疼痛（p = 0.0001）、总体健康（p = 0.0001）、活力（p = 0.0001）和社会功能（p = 0.0003）方面的得分显著更低。与EPS患者相比，该组在总体健康（p = 0.041）和社会功能（p = 0.048）方面的得分也显著更低。与健康志愿者相比，无论疾病类型如何，FD都会导致焦虑水平升高（p = 0.024）。与EPS患者（p = 0.023）和健康志愿者（p = 0.001）相比，PDS患者的抑郁水平升高。
每种类型的FD对社会功能、焦虑和抑郁水平都有一定影响。与EPS患者和健康志愿者相比，PDS患者在心理状态上表现出显著差异。
