Department of Neurology, Gold Coast University Hospital, Southport, QLD 4215, Australia.
Department of Radiology, Gold Coast University Hospital, Southport, QLD 4215, Australia.
J Clin Neurosci. 2020 Feb;72:453-455. doi: 10.1016/j.jocn.2020.01.034. Epub 2020 Jan 22.
A 33-year-old male presented with a progressive four-week history of frontal headache and left visual field impairment. MRI brain confirmed bilateral, asymmetric, occipital vasogenic oedema, suggestive of posterior reversible encephalopathy syndrome (PRES). Serum testing for MOG antibodies was positive, confirming a diagnosis of MOG antibody-related demyelination (MARD). A similar PRES-like pattern of white matter inflammation has been reported previously in neuromyelitis optica spectrum disorder but has not previously been reported in MARD.
一位 33 岁男性，表现为进行性四周的额头痛和左侧视野缺损。脑部 MRI 证实双侧、不对称、枕叶血管源性水肿，提示后部可逆性脑病综合征（PRES）。血清 MO G 抗体检测阳性，确诊为 MO G 抗体相关脱髓鞘疾病（MARD）。此前曾有报道称视神经脊髓炎谱系疾病存在类似 PRES 的脑白质炎症模式，但此前未在 MARD 中报道过。
