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非移植性肝胆或胰腺手术后门静脉肠系膜静脉介入治疗的技术成功率、疗效及安全性评估。

Evaluation of Technical Success, Efficacy, and Safety of Portomesenteric Venous Intervention following Nontransplant Hepatobiliary or Pancreatic Surgery.

作者信息

Mugu Vamshi K, Thompson Scott M, Fleming Chad J, Yohanathan Lavanya, Truty Mark J, Kendrick Michael L, Andrews James C

机构信息

Division of Vascular and Interventional Radiology, Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905.

Division of Vascular and Interventional Radiology, Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905.

出版信息

J Vasc Interv Radiol. 2020 Mar;31(3):416-424.e2. doi: 10.1016/j.jvir.2019.08.011. Epub 2020 Jan 22.

DOI:10.1016/j.jvir.2019.08.011
PMID:31982317
Abstract

PURPOSE

To evaluate technical success, efficacy and safety of portomesenteric venous (PMV) intervention for PMV stenosis or occlusion following nontransplant hepatobiliary or pancreatic (HPB) surgery.

MATERIALS AND METHODS

A retrospective review identified 42 patients (mean age 60 y) with PMV stenosis (n = 33; 79%) or occlusion (n = 9; 21%) who underwent attempted PMV intervention following HPB surgery between June 1, 2011, and April 1, 2018. Main outcomes were technical success, primary patency rates, and complications. Technical success was compared by venous pathology and primary PMV patency based on anticoagulation status after the procedure using Fisher exact test. Rates of primary patency by stent group were estimated using Kaplan-Meier method.

RESULTS

Technical success was 91% (n = 38/42) and significantly higher in patients with stenosis (n = 33/33; 100%) vs occlusion (n = 5/9; 56%) (P = .001). Primary presenting symptom resolved in 28 (87%) patients, including 6 (100%) patients with gastrointestinal bleeding. At mean imaging follow-up of 8.6 months ± 8.8, primary stent patency was 76%. There was no significant difference in primary stent patency based on anticoagulation status after the procedure (P = .48). There were 2 (4.8%) periprocedural complications.

CONCLUSIONS

Portomesenteric venoplasty and stent placement following nontransplant HPB surgery is safe with a high rate of technical success if performed before chronic occlusion.

摘要

目的

评估门静脉肠系膜静脉(PMV)介入治疗非移植性肝胆胰(HPB)手术后PMV狭窄或闭塞的技术成功率、疗效及安全性。

材料与方法

一项回顾性研究纳入了42例患者(平均年龄60岁),这些患者在2011年6月1日至2018年4月1日期间接受HPB手术后出现PMV狭窄(n = 33;79%)或闭塞(n = 9;21%),并尝试进行PMV介入治疗。主要观察指标为技术成功率、原发性通畅率和并发症。采用Fisher精确检验,根据术后抗凝状态,比较静脉病理和原发性PMV通畅情况的技术成功率。使用Kaplan-Meier方法估计支架组的原发性通畅率。

结果

技术成功率为91%(n = 38/42),狭窄患者(n = 33/33;100%)的技术成功率显著高于闭塞患者(n = 5/9;56%)(P = .001)。28例(87%)患者的主要症状得到缓解,其中包括6例(100%)胃肠道出血患者。在平均8.6个月±8.8的影像学随访中,原发性支架通畅率为76%。术后根据抗凝状态,原发性支架通畅率无显著差异(P = .48)。围手术期并发症有2例(4.8%)。

结论

非移植性HPB手术后进行门静脉肠系膜静脉成形术和支架置入术是安全的,若在慢性闭塞前进行,技术成功率较高。

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