真菌 Neosartorya hiratsukae 中的倍半萜吡喃酮、生物碱和双环巴西酰胺。
Meroterpenoid pyrones, alkaloid and bicyclic brasiliamide from the fungus Neosartorya hiratsukae.
机构信息
Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Department of Biology, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.
出版信息
Fitoterapia. 2020 Apr;142:104485. doi: 10.1016/j.fitote.2020.104485. Epub 2020 Jan 23.
Two new meroterpenoid pyrones, chevalone G (1) and aszonapyrone C (2), a new indole alkaloid, 7-chlorofischerindoline (3) and a new bicyclic brasiliamide, brasiliamide H (4), together with sixteen known compounds, 5-20 were isolated from the fungus Neosartorya hiratsukae. Their structures were established on the basis of spectroscopic evidence. The antibacterial activity and the cytotoxic activity of new compounds were evaluated.
从真菌 Neosartorya hiratsukae 中分离得到两个新的倍半萜吡喃酮 chevalone G (1) 和 aszonapyrone C (2)、一个新的吲哚生物碱 7-氯 Fischerindoline (3) 和一个新的双环巴西酰胺 brasiliamide H (4)，以及十六个已知化合物 5-20。基于光谱证据确定了它们的结构。评估了新化合物的抗菌活性和细胞毒性活性。
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