Aberrant global and local efficiency of the executive subnetwork in essential tremor.

This study aims to use probabilistic tractography to ascertain the global (GE) and local efficiency (LE) of the executive subnetwork in essential tremor (ET). Significantly lower GE of the whole executive subnetwork and lower LE of the left rostral middle frontal gyrus, frontal pole, inferior frontal gyrus, bilateral anterior cingulate cortex, and medial orbitofrontal cortex. These results imply ineffective and inadequate communication of the executive subnetwork, and may be causally associated with the executive dysfunction observed in ET.