Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashiku, Hamamatsu, Shizuoka, 431-3192, Japan.
Department of Orthopedic Surgery and Division of Geriatric Musculoskeletal Health, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Eur Spine J. 2020 Apr;29(4):860-869. doi: 10.1007/s00586-020-06300-2. Epub 2020 Jan 25.
Gastroesophageal reflux disease (GERD) is reported as one of the symptoms of adult spinal deformity (ASD). Little is known about the mid- to long-term improvement in GERD symptoms after ASD surgery. Therefore, this retrospective study from prospectively collected database aimed to investigate GERD symptoms in patients for a minimum of 2 years after ASD corrective surgery.
Records from 230 patients (mean age: 64 years) who underwent ASD surgery were examined using the frequency scale for the symptoms of GERD (FSSG) questionnaires for the diagnosis of GERD. FSSG scores and radiographic parameters were investigated preoperatively and postoperatively at 6 months and 1, 2, and 5 years.
In total, 90 (39%) patients were preoperatively diagnosed with GERD defined by FSSG score ≥ 8 points. Radiographic results showed that the corrective surgeries improved local and global alignments. In the GERD patients, preoperative FSSG scores (16.1 ± 7.3 points) significantly improved to 7.7 ± 7.4 points within 6 months postoperatively (p < 0.001), and postoperative FSSG scores maintained at 1 year (9.9 ± 8.2 points, p = 0.061), 2 years (9.7 ± 8.2 points, p = 0.086), and 5 years (9.4 ± 8.0 points, p = 0.177). Among the GERD group, 62 patients (69%; improvement cases) showed improvement in GERD symptoms defined by FSSG score < 8 points within 6 months postoperatively.
Among ASD patients, 39% were diagnosed with GERD. In 69% of these patients, GERD symptoms improved within 6 months of corrective surgery and maintained up to 5 years postoperatively. These slides can be retrieved under Electronic Supplementary Material.
胃食管反流病（GERD）被报道为成人脊柱畸形（ASD）的症状之一。对于 ASD 手术后 GERD 症状的中期至长期改善知之甚少。因此，本项来自前瞻性收集数据库的回顾性研究旨在调查 ASD 矫正手术后至少 2 年患者的 GERD 症状。
使用胃食管反流病症状频率量表（FSSG）问卷对 230 例（平均年龄：64 岁）接受 ASD 手术患者的记录进行检查，以诊断 GERD。FSSG 评分和影像学参数在术前和术后 6 个月、1 年、2 年和 5 年进行检查。
共有 90 例（39%）患者术前通过 FSSG 评分≥8 分被诊断为 GERD。影像学结果显示矫正手术改善了局部和整体的排列。在 GERD 患者中，术前 FSSG 评分（16.1±7.3 分）在术后 6 个月内显著改善至 7.7±7.4 分（p<0.001），术后 FSSG 评分在 1 年（9.9±8.2 分，p=0.061）、2 年（9.7±8.2 分，p=0.086）和 5 年（9.4±8.0 分，p=0.177）时保持稳定。在 GERD 组中，有 62 例（69%；改善病例）在术后 6 个月内 FSSG 评分<8 分，GERD 症状得到改善。
在 ASD 患者中，有 39%被诊断为 GERD。在这些患者中，有 69%的患者在矫正手术后 6 个月内 GERD 症状得到改善，并在术后 5 年内保持稳定。这些幻灯片可以在电子补充材料中检索到。
