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本文引用的文献

1
"We don't got that kind of time, man. We're trying to get high!": Exploring potential use of drug checking technologies among structurally vulnerable people who use drugs.“我们没时间了,伙计。我们想嗨起来!”:探索药物检测技术在结构脆弱的吸毒者中的潜在用途。
Int J Drug Policy. 2019 Sep;71:125-132. doi: 10.1016/j.drugpo.2019.06.018. Epub 2019 Jul 20.
2
Acceptability of implementing community-based drug checking services for people who use drugs in three United States cities: Baltimore, Boston and Providence.在美国三个城市(巴尔的摩、波士顿和普罗维登斯)实施基于社区的毒品检测服务对吸毒者的可接受性。
Int J Drug Policy. 2019 Jun;68:46-53. doi: 10.1016/j.drugpo.2019.03.003. Epub 2019 Apr 13.
3
Trusting the source: The potential role of drug dealers in reducing drug-related harms via drug checking.信任来源:毒贩通过毒品检测在减少毒品相关危害方面的潜在作用。
Drug Alcohol Depend. 2019 May 1;198:1-6. doi: 10.1016/j.drugalcdep.2019.01.035. Epub 2019 Mar 6.
4
Public health responses to the opioid crisis in North America.北美针对阿片类药物危机的公共卫生应对措施。
J Epidemiol Community Health. 2019 May;73(5):377-378. doi: 10.1136/jech-2018-210599. Epub 2019 Feb 5.
5
Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States.预防美国处方类阿片药物滥用和预计的过量死亡。
JAMA Netw Open. 2019 Feb 1;2(2):e187621. doi: 10.1001/jamanetworkopen.2018.7621.
6
Use of rapid fentanyl test strips among young adults who use drugs.快速芬太尼检测条在药物使用的青年中的使用情况。
Int J Drug Policy. 2018 Nov;61:52-58. doi: 10.1016/j.drugpo.2018.09.009. Epub 2018 Oct 18.
7
Evaluation of a fentanyl drug checking service for clients of a supervised injection facility, Vancouver, Canada.评估加拿大温哥华监督注射设施的使用者的芬太尼药物检测服务。
Harm Reduct J. 2018 Sep 10;15(1):46. doi: 10.1186/s12954-018-0252-8.
8
Initial results of a drug checking pilot program to detect fentanyl adulteration in a Canadian setting.一项药物检测试点项目的初步结果,旨在检测加拿大的芬太尼掺假情况。
Drug Alcohol Depend. 2018 Sep 1;190:242-245. doi: 10.1016/j.drugalcdep.2018.06.020. Epub 2018 Jul 24.
9
Notes from the Field: Overdose Deaths with Carfentanil and Other Fentanyl Analogs Detected - 10 States, July 2016-June 2017.实地记录:2016年7月至2017年6月期间在10个州检测到的使用卡芬太尼和其他芬太尼类似物导致的过量用药死亡情况
MMWR Morb Mortal Wkly Rep. 2018 Jul 13;67(27):767-768. doi: 10.15585/mmwr.mm6727a4.
10
Strategies for Reducing Opioid-Overdose Deaths - Lessons from Canada.减少阿片类药物过量死亡的策略——来自加拿大的经验教训
N Engl J Med. 2018 Apr 26;378(17):1565-1567. doi: 10.1056/NEJMp1800216.

加拿大温哥华目击过量使用对滥用非法药物者使用药物检测服务的影响。

Effect of witnessing an overdose on the use of drug checking services among people who use illicit drugs in Vancouver, Canada.

机构信息

, British Columbia Centre on Substance Use , Vancouver, BC, Canada.

Graduate Programs in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia , Vancouver, BC, Canada.

出版信息

Am J Drug Alcohol Abuse. 2020 Jul 3;46(4):506-511. doi: 10.1080/00952990.2019.1708087. Epub 2020 Jan 26.

DOI:10.1080/00952990.2019.1708087
PMID:31983241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7382612/
Abstract

BACKGROUND

Since 2013, fentanyl-contaminated drugs have been driving North America's opioid-overdose epidemic. Drug checking, which enables people who use illicit drugs (PWUD) to test and receive feedback regarding the contents of their drugs, is being considered as a potential tool to address the toxic drug supply. While some PWUD witness overdoses, little is known about the impact of these experiences on subsequent risk reduction practices.

OBJECTIVE

The purpose of this study was to examine the effect of witnessing an overdose on drug checking service use.

METHODS

Data were derived from prospective cohorts of PWUD in Vancouver, Canada, a setting with a community-wide fentanyl overdose crisis, between June 1, 2018 and December 1, 2018. Multivariable logistic regression was used to estimate the effect of witnessing an overdose on drug checking service use.

RESULTS

1,426 participants were eligible for the study, including 530 females; 767 (53.8%) participants reported witnessing an overdose and 196 (13.7%) reported using drug checking services in the last 6 months. In multivariable analyses, after adjusting for a range of confounders including the use of fentanyl, witnessing an overdose was positively associated with drug checking service use (adjusted odds ratio = 2.32; 95% confidence interval: 1.57-3.49).

CONCLUSION

Our findings suggest that witnessing an overdose may motivate PWUD to use drug checking services. Given that only a small proportion of PWUD in the study reported using drug checking services, our findings highlight the need to continue to scale-up a range of overdose prevention interventions.

摘要

背景

自 2013 年以来,芬太尼污染的毒品一直推动着北美阿片类药物过量流行。药物检测使使用非法药物的人(PWUD)能够测试并收到有关其药物内容的反馈,被认为是解决有毒药物供应的潜在工具。虽然一些 PWUD 目睹了过量用药,但人们对这些经历对随后的减少风险行为的影响知之甚少。

目的

本研究旨在检验目睹过量用药对药物检测服务使用的影响。

方法

数据来自 2018 年 6 月 1 日至 2018 年 12 月 1 日期间加拿大温哥华的前瞻性 PWUD 队列,这是一个社区范围内芬太尼过量危机的环境。多变量逻辑回归用于估计目睹过量用药对药物检测服务使用的影响。

结果

共有 1426 名符合条件的参与者,包括 530 名女性;767(53.8%)名参与者报告目睹了过量用药,196(13.7%)名参与者报告在过去 6 个月内使用了药物检测服务。在多变量分析中,调整了包括使用芬太尼在内的一系列混杂因素后,目睹过量用药与药物检测服务使用呈正相关(调整后的优势比=2.32;95%置信区间:1.57-3.49)。

结论

我们的研究结果表明,目睹过量用药可能会促使 PWUD 使用药物检测服务。鉴于研究中只有一小部分 PWUD 报告使用了药物检测服务,我们的研究结果突出表明需要继续扩大一系列的过量预防干预措施。