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色素性紫癜性皮病:文献复习。

Pigmented Purpuric Dermatosis: A Review of the Literature.

机构信息

Servicio de Dermatología y Venereología, Hospital Clínico Lozano Blesa, Zaragoza, España.

Servicio de Dermatología y Venereología, Hospital Clínico Lozano Blesa, Zaragoza, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2020 Apr;111(3):196-204. doi: 10.1016/j.ad.2019.02.013. Epub 2020 Jan 23.

Abstract

The pigmented purpuric dermatoses are a group of benign, chronic diseases. The variants described to date represent different clinical presentations of the same entity, all having similar histopathologic characteristics. We provide an overview of the most common PPDs and describe their clinical, dermatopathologic, and epiluminescence features. PPDs are both rare and benign, and this, together with an as yet poor understanding of the pathogenic mechanisms involved, means that no standardized treatments exist. We review the treatments described to date. However, because most of the descriptions are based on isolated cases or small series, there is insufficient evidence to support the use of any of these treatments as first-line therapy.

摘要

色素性紫癜性皮肤病是一组良性、慢性疾病。迄今为止描述的各种变体代表了同一实体的不同临床表现,均具有相似的组织病理学特征。我们概述了最常见的 PPD,并描述了它们的临床、皮肤病理学和表皮荧光特征。PPD 既罕见又良性,而且由于对涉及的发病机制了解甚少,这意味着目前还没有标准化的治疗方法。我们回顾了迄今为止描述的治疗方法。然而,由于大多数描述都是基于孤立的病例或小系列,因此没有足够的证据支持将这些治疗方法中的任何一种作为一线治疗。

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