Department of Nephrology, St George Hospital, Sydney, New South Wales, Australia.
Department of Nephrology, St George Hospital, Sydney, New South Wales, Australia.
J Ren Nutr. 2020 Sep;30(5):368-379. doi: 10.1053/j.jrn.2019.11.004. Epub 2020 Jan 24.
One of the most disabling, yet neglected, symptom of patients with chronic kidney disease (CKD) is alteration in taste. The purpose of this review is to examine the extent and content of research around this symptom in CKD with the goals of (1) identifying gaps in current research knowledge and (2) guiding future research. The review summarizes the basic anatomy and physiology of taste followed by analysis of the epidemiology, pathophysiology, and management strategies for taste changes in patients with CKD.
慢性肾脏病（CKD）患者有一种最具致残性但却被忽视的症状，即味觉改变。本文旨在探讨 CKD 患者味觉障碍相关研究的广度和内容，目的在于（1）发现当前研究知识中的空白，（2）指导未来的研究。本文首先概述了味觉的基本解剖学和生理学，然后分析了 CKD 患者味觉变化的流行病学、病理生理学和管理策略。
