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极低出生体重儿的追赶生长及相关因素

[Catch-up growth and associated factors in very low birth weight infants].

作者信息

Durá-Travé Teodoro, San Martín-García Isabel, Gallinas-Victoriano Fidel, Chueca Guindulain María Jesús, Berrade-Zubiri Sara

机构信息

Departamento de Pediatría, Facultad de Medicina, Universidad de Navarra, Pamplona, Navarra, España; Servicio de Pediatría, Complejo Hospitalario de Navarra, Pamplona, Navarra, España; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Navarra, España.

Servicio de Pediatría, Complejo Hospitalario de Navarra, Pamplona, Navarra, España.

出版信息

An Pediatr (Engl Ed). 2020 Nov;93(5):282-288. doi: 10.1016/j.anpedi.2019.06.017. Epub 2020 Jan 23.

Abstract

INTRODUCTION

The characteristics of catch-up growth in very low birth weight infants (VLBW) have not been clearly established. The aim of this study was to analyse the height catch-up and some associated factors in a cohort of VLBW (birth weight<1,500g) from birth to age 14 years.

METHODS

We obtained retrospective data on weight and height at birth and ages one, 2, 3, 4, 6, 8, 10, 12 and 14 years in a cohort of 170 VLBW. We compared these anthropometric values with those documented in a control group.

RESULTS

Thirty-seven children (21.8%) were born with an extremely low birth weight and 32 (18.8%) extremely preterm. At 10 years of age, 7% of VLBW (1,000-1,500g) and 35% of extremely low birth weight (<1,500g) children had short stature (P=.001). Almost all VLBW children who had a normal height at ages 2, 4 and 10 years had exhibited adequate weight catch-up in previous evaluations. We found that extremely low birth weight and extremely preterm were independent predictors for inadequate height catch-up.

CONCLUSION

The growth pattern of VLBW children has specific characteristics. The catch-up in weight seems to be an important factor for catch-up in height, and therefore a thorough nutritional follow-up is recommended in these children.

摘要

引言

极低出生体重儿(VLBW)追赶生长的特征尚未明确。本研究旨在分析一组出生体重<1500g的极低出生体重儿从出生到14岁的身高追赶情况及一些相关因素。

方法

我们获取了170名极低出生体重儿队列中出生时、1岁、2岁、3岁、4岁、6岁、8岁、10岁、12岁和14岁时体重和身高的回顾性数据。我们将这些人体测量值与对照组记录的数据进行了比较。

结果

37名儿童(21.8%)出生时为超低出生体重,32名(18.8%)为极早产儿。10岁时,1000 - 1500g的极低出生体重儿中有7%,超低出生体重(<1500g)儿童中有35%身材矮小(P = 0.001)。几乎所有在2岁、4岁和10岁时身高正常的极低出生体重儿在之前的评估中体重追赶情况良好。我们发现超低出生体重和极早产是身高追赶不足的独立预测因素。

结论

极低出生体重儿的生长模式具有特定特征。体重追赶似乎是身高追赶的一个重要因素,因此建议对这些儿童进行全面的营养随访。

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