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有继发性不孕且有症状性剖宫产瘢痕憩室的患者接受宫腔镜下憩室切除术的生育成功率。

Fertility success rates in patients with secondary infertility and symptomatic cesarean scar niche undergoing hysteroscopic niche resection.

作者信息

Cohen Shlomo B, Bouaziz Jerome, Bar On Alexandra, Orvieto Raoul

机构信息

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Hashomer, Israel.

Herzliya Medical Center, Herzliya, Israel.

出版信息

Gynecol Endocrinol. 2020 Oct;36(10):912-916. doi: 10.1080/09513590.2020.1716327. Epub 2020 Jan 27.

Abstract

Cesarean-induced niche can cause symptoms such as abnormal postmenstrual bleeding, pain, and associated infertility. Although hysteroscopic niche resection is generally considered an effective treatment to control abnormal uterine bleeding, the impact of surgical resection on fertility outcomes is still uncertain. In the present study, we aimed to evaluate the fertility outcomes of symptomatic patients following hysteroscopic niche resection. The design in this retrospective cohort study is Canadian Task Force classification II-2 and it is carried out in a tertiary medical center (Tel-Hashomer) and a private medical center (Herzliya), both in Israel. We included all patients who underwent a niche resection between 2011 and 2015 following at least one year of infertility. From 2011 to 2015, 39 patients with a symptomatic niche and secondary infertility were treated by hysteroscopic niche resection. The patients' mean age was 37.2 (34-41) years, mean number of gestations was 7.04 (1-16), and mean parity 5.1 (1-14). The mean number of previous cesarean sections was 3.4 (1-6). Before the surgery, 32 patients attempted and failed to conceive spontaneously and seven patients underwent fertilization (IVF) treatment and failed. One year after the hysteroscopic resection, 18 patients conceived (14 spontaneously and four following IVF), leading to a cumulative pregnancy rate of 46.15%. Among the patients who failed to conceive after at least two IVF cycles prior to the hysteroscopic resection, 42.8% conceived following surgery (three patients out of seven). Hysteroscopic niche resection should be considered an effective treatment in patients suffering from secondary infertility.PrécisHysteroscopic niche resection is a safe option for patients with symptomatic secondary infertility, resulting in acceptable fertility rates.

摘要

剖宫产瘢痕憩室可导致月经后异常出血、疼痛及相关不孕等症状。尽管宫腔镜下瘢痕憩室切除术通常被认为是控制子宫异常出血的有效治疗方法,但手术切除对生育结局的影响仍不确定。在本研究中,我们旨在评估有症状患者宫腔镜下瘢痕憩室切除术后的生育结局。本回顾性队列研究的设计为加拿大工作组分类II-2级,在以色列的一家三级医疗中心(特拉维夫哈绍默医院)和一家私立医疗中心(赫兹利亚医疗中心)进行。我们纳入了2011年至2015年间在经历至少一年不孕后接受瘢痕憩室切除术的所有患者。2011年至2015年期间,39例有症状瘢痕憩室和继发性不孕的患者接受了宫腔镜下瘢痕憩室切除术。患者的平均年龄为37.2(34 - 41)岁,平均妊娠次数为7.04(1 - 16)次,平均产次为5.1(1 - 14)次。既往剖宫产的平均次数为3.4(1 - 6)次。手术前,32例患者尝试自然受孕但失败,7例患者接受体外受精(IVF)治疗但失败。宫腔镜切除术后一年,18例患者怀孕(14例自然受孕和4例IVF后受孕),累积妊娠率为46.15%。在宫腔镜切除术前至少经历两个IVF周期仍未受孕的患者中,42.8%在手术后受孕(7例中有3例)。宫腔镜下瘢痕憩室切除术应被视为治疗继发性不孕患者的有效方法。

摘要

宫腔镜下瘢痕憩室切除术对于有症状的继发性不孕患者是一种安全的选择,可带来可接受的生育率。

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