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一种使用微波反应器进行有机转化的绿色方法。

A Green Approach for Organic Transformations Using Microwave Reactor.

作者信息

Das Subrata, Banik Rupak, Kumar Brajesh, Roy Subhadip, Amhad Khursheed, Sukul Pradip K

机构信息

Department of Chemistry, National Institute of Technology, Panta 800005, India.

Department of Chemistry, National Institute of Technology Agartala 799046, India.

出版信息

Curr Org Synth. 2019;16(5):730-764. doi: 10.2174/1570179416666190412160048.

Abstract

Microwave-assisted organic transformation (MAOR) is presently gaining wide popularity in the field of organic synthesis. The conventional heating technique is gradually being removed from the laboratory and a novel microwave heating technique established to be used in both academia and industry. As compared to the classical organic methodology, the green technology tools have several advantages like dramatically reduced reaction times, improved yields, site selectivity, and the increased product purities with simplification of work-up procedures. In the current study, we have briefly described the overview of recent developments and applications of microwave irradiation in organic transformation with schematic compiling of the organic reactions, bioactive heterocyclic compounds, and so on. This review also presents a critical analysis of the various advantages of microwave irradiation in organic synthesis/transformation compared to the classical or conventional heating. So, we believe that our current study of the green microwave heating technique will be highly beneficial for the researchers from both academia and industry in their near future.

摘要

微波辅助有机转化(MAOR)目前在有机合成领域正变得越来越受欢迎。传统加热技术正逐渐从实验室中被淘汰,一种新型微波加热技术已被确立用于学术界和工业界。与经典有机方法相比,绿色技术工具具有多个优点,如显著缩短反应时间、提高产率、位点选择性,以及通过简化后处理程序提高产品纯度。在当前研究中,我们简要描述了微波辐射在有机转化方面的最新进展和应用概述,并对有机反应、生物活性杂环化合物等进行了示意性汇编。本综述还对微波辐射在有机合成/转化中相对于经典或传统加热的各种优点进行了批判性分析。因此,我们相信我们目前对绿色微波加热技术的研究将在不久的将来对学术界和工业界的研究人员非常有益。

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