Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Department of Pharmacology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
J Periodontol. 2020 Sep;91(9):1177-1185. doi: 10.1002/JPER.19-0464. Epub 2020 Feb 14.
Effectiveness of scaling and root planing (SRP) with/without adjunct probiotic (Lactobacillus reuteri) treatment towards the reduction in periodontal inflammatory parameters (clinical attachment loss [AL], marginal bone loss [MBL], plaque index [PI], and bleeding on probing [BOP] in shamma users and non-users [controls] with chronic periodontitis [CP]) remains uninvestigated. The aim of the present randomized controlled trial was to compare the efficacy of SRP with and without adjunct probiotic therapy (PT) in the treatment of CP among shamma users and controls (individuals not using tobacco in any form).
The study was conducted in accordance with the Consolidated Standards of Reporting Trials guidelines. Patient demographics were recorded using a questionnaire. Therapeutically, patients were allotted into four groups as follows: 1) group 1: Shamma chewers that underwent SRP alone; 2) group 2: Shamma-chewers that underwent SRP + PT; 3) group 3: Non-chewers that underwent SRP alone; and 4) group 4: Non-chewers that underwent SRP + PT. Periodontal parameters (PI, BOP, PD, clinical AL and mesial and distal MBL) were measured on all teeth except third molars at baseline and at 3- and 6-month follow-ups. Level of significance was set at P < 0.05.
In total, 31, 32, 31, and 33 individuals were included in groups 1, 2, 3, and 4, respectively. Among shamma users, there was no significant difference in the scores of PI, BOP, PD, clinical AL and MBL when SRP was performed with/without adjunct PT. Amongst controls, SRP with adjunct PT was more effective in reducing PI (P < 0.05), BOP (P < 0.05) and PD (P < 0.05) at 3-month follow-up. There was no significant difference in periodontal parameters at 3- and 6-month follow-ups in patients that underwent SRP with and without adjunct PT.
Habitual shamma use compromises the outcome of SRP in patients with CP. Among patients that do not use any form of ST product, SRP is an effective treatment modality for the treatment of CP, and this relationship is independent of use of adjunct PT.
在使用/不使用辅助益生菌（鼠李糖乳杆菌）治疗的情况下，刮治和根面平整（SRP）对减少牙周炎炎症参数（临床附着丧失[AL]、边缘骨丧失[MBL]、菌斑指数[PI]和探诊出血[BOP]）的效果在 shamma 使用者和非使用者（慢性牙周炎[CP]的对照者[未使用任何形式烟草的个体]）中仍未得到研究。本随机对照试验的目的是比较 SRP 联合和不联合辅助益生菌治疗（PT）在 shamma 使用者和对照者（未使用任何形式烟草的个体）CP 治疗中的疗效。
该研究符合《CONSORT 报告标准指南》。使用问卷记录患者的人口统计学数据。治疗上，患者被分配到以下四组：1）组 1：接受单独 SRP 的 shamma 咀嚼者；2）组 2：接受 SRP+PT 的 shamma 咀嚼者；3）组 3：接受单独 SRP 的非咀嚼者；4）组 4：接受 SRP+PT 的非咀嚼者。在基线和 3 个月和 6 个月随访时，测量所有牙齿（第三磨牙除外）的牙周参数（PI、BOP、PD、临床 AL 和近中及远中 MBL）。显著性水平设为 P<0.05。
在组 1、2、3 和 4 中，分别有 31、32、31 和 33 人。在 shamma 使用者中，当单独进行 SRP 时，PI、BOP、PD、临床 AL 和 MBL 的评分没有差异。在对照组中，SRP 联合辅助 PT 在 3 个月随访时更有效降低 PI（P<0.05）、BOP（P<0.05）和 PD（P<0.05）。在接受单独 SRP 和辅助 PT 的患者中，3 个月和 6 个月随访时牙周参数无显著差异。
习惯性咀嚼 shamma 会影响 CP 患者的 SRP 效果。在不使用任何形式 ST 产品的患者中，SRP 是治疗 CP 的有效治疗方法，这种关系独立于辅助 PT 的使用。
