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益生菌作为牙周炎治疗的辅助疗法——现实还是幻想——临床视角

Probiotics as an adjunctive therapy in periodontitis treatment-reality or illusion-a clinical perspective.

作者信息

Baddouri Lamyae, Hannig Matthias

机构信息

Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Homburg, Germany.

Pharmacy, Saarland University, Saarbrucken, Germany.

出版信息

NPJ Biofilms Microbiomes. 2024 Dec 16;10(1):148. doi: 10.1038/s41522-024-00614-5.

DOI:10.1038/s41522-024-00614-5
PMID:39681550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11649906/
Abstract

Periodontitis, a prevalent oral health issue, involves various microorganisms and clinical effects. This review examines probiotics as adjunctive therapy for periodontitis by analyzing forty clinical studies. Findings showed mixed results due to differences in study design, probiotic types, and clinical parameters; however, probiotics improved outcomes in severe cases. Caution is advised when interpreting these results, as longer follow-up periods reveal variability and potential regression in effects.

摘要

牙周炎是一种常见的口腔健康问题,涉及多种微生物和临床影响。本综述通过分析40项临床研究,探讨了益生菌作为牙周炎辅助治疗的效果。研究结果显示,由于研究设计、益生菌类型和临床参数的差异,结果喜忧参半;然而,益生菌在严重病例中改善了治疗效果。在解释这些结果时建议谨慎,因为更长的随访期显示出效果的变异性和潜在的回归性。

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