Carnegie Mellon University, Pittsburgh, PA, USA.
Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN, USA.
Pediatr Transplant. 2020 May;24(3):e13655. doi: 10.1111/petr.13655. Epub 2020 Jan 27.
The high discard rate of pediatric donor hearts presents a major challenge for children awaiting heart transplantation. Recent literature identifies several factors that contribute to the disparities in pediatric donor heart usage, including regulatory oversight, the absence of guidelines on pediatric donor heart acceptance, and variation among transplant programs. However, a likely additional contributor to this issue are the behavioral factors influencing transplant team decisions in donor offer scenarios, a topic that has not yet been studied in detail. Behavioral economics and decision psychology provide an excellent foundation for investigating decision-making in the pediatric transplant setting, offering key insights into the behavior of transplant professionals. We conducted a systematic review of published literature in pediatric heart transplant related to behavioral economics and the psychology of decision-making. In this review, we draw on paradigms from these two domains in order to examine how existing aspects of the transplant environment, including regulatory oversight, programmatic variation, and allocation systems, may precipitate potential biases surrounding donor offer decisions. Recognizing how human decision behavior influences donor acceptance is a first step toward improving utilization of potentially viable pediatric donor hearts.
儿科供体心脏的高淘汰率对等待心脏移植的儿童构成了重大挑战。最近的文献确定了导致儿科供体心脏使用差异的几个因素,包括监管监督、缺乏儿科供体心脏接受的指导方针以及移植项目之间的差异。然而,造成这一问题的一个可能的额外因素是影响供体提供情况下移植团队决策的行为因素,这个问题尚未得到详细研究。行为经济学和决策心理学为研究儿科移植环境中的决策提供了一个极好的基础,为移植专业人员的行为提供了关键的见解。我们对与行为经济学和决策心理学相关的儿科心脏移植相关的已发表文献进行了系统回顾。在本综述中,我们借鉴了这两个领域的范例,以研究移植环境中的现有方面,包括监管监督、项目差异和分配系统,如何可能引发供体提供决策方面的潜在偏见。认识到人类决策行为如何影响供体接受是提高潜在可行儿科供体心脏利用率的第一步。