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供体心脏提供给儿科候补候选人的废弃和/或拒绝率的回顾。

Review of the discard and/or refusal rate of offered donor hearts to pediatric waitlisted candidates.

机构信息

Division of Cardiac Surgery, Pediatric Heart Center, University Children's Hospital Zurich, Zurich, Switzerland.

Children's Hospital Colorado, Denver, CO, USA.

出版信息

Pediatr Transplant. 2020 May;24(3):e13674. doi: 10.1111/petr.13674. Epub 2020 Mar 21.

Abstract

We aimed to review current literature on the discard rate of donor hearts offered to pediatric recipients and assess geographical differences. Consequences and ways to reduce the discard rate are discussed. A systemic review on published literature on pediatric transplantation published in English since 2010 was undertaken. Additionally, a survey was sent to international OPOs with the goal of incorporating responses from around the world providing a more global picture. Based on the literature review and survey, there is a remarkably wide range of discard and/or refusal for pediatric hearts offered for transplant, ranging between 18% and 57% with great geographic variation. The data suggest that that the overall refusal rate may have decreased over the last decade. Reasons for organ discard were difficult to identify from the available data. Although the refusal rate of pediatric donor hearts seems to be lower compared to that reported in adults, it is still as high as 57% with geographic variation.

摘要

我们旨在回顾目前关于提供给儿科受者的供体心脏废弃率的文献,并评估地域差异。讨论了后果和降低废弃率的方法。对自 2010 年以来以英文发表的儿科移植的已出版文献进行了系统综述。此外,还向国际 OPO 发送了一份调查,目的是纳入来自世界各地的回复,提供更全面的情况。根据文献综述和调查,供移植的儿科心脏的废弃率和/或拒绝率差异很大,范围在 18%至 57%之间,地域差异很大。数据表明,过去十年中,整体拒绝率可能有所下降。从现有数据中很难确定器官废弃的原因。尽管与成人报道的相比,儿科供体心脏的拒绝率似乎较低,但仍高达 57%,且存在地域差异。

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