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根据年龄相关性黄斑变性亚型评估玻璃体内注气对黄斑下出血的预后影响。

VISUAL PROGNOSIS AFTER PNEUMATIC DISPLACEMENT OF SUBMACULAR HEMORRHAGE ACCORDING TO AGE-RELATED MACULAR DEGENERATION SUBTYPES.

机构信息

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; and.

Catholic Institute for Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

Retina. 2020 Dec;40(12):2304-2311. doi: 10.1097/IAE.0000000000002762.

Abstract

PURPOSE

This study compared the visual outcome after pneumatic displacement of submacular hemorrhage among patients with different subtypes of age-related macular degeneration (AMD).

METHODS

We retrospectively reviewed the medical records of 67 patients (67 eyes) who underwent treatment for submacular hemorrhage associated with AMD. All the patients underwent pneumatic displacement. Demographic parameters, visual acuity, and anatomical features were analyzed among AMD subtypes: typical AMD, polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP).

RESULTS

Among the eyes with submacular hemorrhage, 24, 30, and 13 eyes had typical AMD, PCV, and RAP, respectively. Post-treatment best-corrected visual acuity was best in the PCV group and worst in the RAP group (P < 0.001). The proportion of eyes with improved visual acuity was highest in the PCV subtype and lowest in the RAP subtype (P = 0.044). Logistic regression analysis showed that AMD subtype (P = 0.016) and time to treatment (<7 days) (P = 0.037) are associated with the final visual outcome.

CONCLUSION

The final post-treatment visual outcome after the incidence of submacular hemorrhage was best in the PCV group and worst in the RAP group. Age-related macular degeneration subtype is a significant factor associated with the visual prognosis of submacular hemorrhage.

摘要

目的

本研究比较了不同类型年龄相关性黄斑变性(AMD)患者黄斑下出血行气动移位术后的视力结果。

方法

我们回顾性分析了 67 例(67 只眼)接受黄斑下出血相关 AMD 治疗患者的病历。所有患者均行气动移位术。分析 AMD 各亚型(典型 AMD、息肉样脉络膜血管病变(PCV)和视网膜血管性增殖(RAP))的人口统计学参数、视力和解剖特征。

结果

黄斑下出血眼中分别有 24、30 和 13 只眼为典型 AMD、PCV 和 RAP。治疗后最佳矫正视力在 PCV 组最佳,RAP 组最差(P<0.001)。视力提高的比例在 PCV 亚型中最高,RAP 亚型中最低(P=0.044)。Logistic 回归分析显示,AMD 亚型(P=0.016)和治疗时间(<7 天)(P=0.037)与最终视力结果相关。

结论

黄斑下出血发生后,治疗后最终视力结果在 PCV 组最佳,RAP 组最差。AMD 亚型是黄斑下出血视力预后的重要因素。

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