• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

氮杂并苯超强碱作为用于酸性分析物的基质辅助激光解吸/电离质谱（MAILD）基质

Azahelicene Superbases as MAILD Matrices for Acidic Analytes.

作者信息

Napagoda Mayuri, Rulíšek Lubomír, Jančařík Andrej, Klívar Jiří, Šámal Michal, Stará Irena G, Starý Ivo, Šolínová Veronika, Kašička Václav, Svatoš Aleš

机构信息

Mass Spectrometry/Proteomics Research Group, Max Planck Institute for Chemical Ecology, Hans-Knoell-Strasse 8, 07745 Jena (Germany), Fax: (+49) 3641-571701.

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578.

出版信息

Chempluschem. 2013 Sep;78(9):937-942. doi: 10.1002/cplu.201300258. Epub 2013 Aug 19.

DOI:10.1002/cplu.201300258
PMID:31986738
Abstract

Fitting the profile: A superbasic 1,14-diaza[5]helicene can serve as an efficient, ionless matrix for matrix-assisted ionization/laser desorption (MAILD) spectrometry. The matrix outperforms other bases by acting as a kinetically active proton sponge and is highly suitable for high-throughput metabolomics analysis. There is a correlation between the basicity (and proton-sponge character) of matrices and their efficacy in MAILD-MS.

摘要

符合要求

一种超碱性的1,14-二氮杂[5]并苯可作为基质辅助电离/激光解吸（MAILD）质谱分析的高效无离子基质。该基质作为一种具有动力学活性的质子海绵，性能优于其他碱，非常适合高通量代谢组学分析。基质的碱性（和质子海绵特性）与其在MAILD-MS中的功效之间存在相关性。

相似文献

1
Azahelicene Superbases as MAILD Matrices for Acidic Analytes.氮杂并苯超强碱作为用于酸性分析物的基质辅助激光解吸/电离质谱（MAILD）基质
Chempluschem. 2013 Sep;78(9):937-942. doi: 10.1002/cplu.201300258. Epub 2013 Aug 19.
2
Superbasic alkyl-substituted bisphosphazene proton sponges: a new class of deprotonating matrices for negative ion matrix-assisted ionization/laser desorption mass spectrometry of low molecular weight hardly ionizable analytes.超碱性烷基取代双磷腈质子海绵：用于低分子量难电离分析物负离子基质辅助电离/激光解吸质谱的一类新型去质子化基质。
Rapid Commun Mass Spectrom. 2016 Jul 30;30(14):1680-1686. doi: 10.1002/rcm.7604.
3
Structural Characterization of Neutral Saccharides by Negative Ion MALDI Mass Spectrometry Using a Superbasic Proton Sponge as Deprotonating Matrix.采用超强碱性质子海绵作为去质子化基质的负离子 MALDI 质谱法对中性糖进行结构表征。
J Am Soc Mass Spectrom. 2017 Aug;28(8):1666-1675. doi: 10.1007/s13361-017-1679-y. Epub 2017 May 2.
4
Furoic and mefenamic acids as new matrices for matrix assisted laser desorption/ionization-(MALDI)-mass spectrometry.呋喃甲酸和甲芬那酸作为基质辅助激光解吸/电离-（MALDI）-质谱的新基质。
Talanta. 2013 Oct 15;115:442-50. doi: 10.1016/j.talanta.2013.05.050. Epub 2013 May 28.
5
Quantitative detection of trace perfluorinated compounds in environmental water samples by Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry with 1,8-bis(tetramethylguanidino)-naphthalene as matrix.采用 1,8-双（四甲基胍基）-萘作为基质的基质辅助激光解吸/电离-飞行时间质谱法对环境水样中的痕量全氟化合物进行定量检测。
Talanta. 2011 Jul 15;85(1):345-52. doi: 10.1016/j.talanta.2011.03.062. Epub 2011 Apr 5.
6
Polyamine co-matrices for matrix-assisted laser desorption/ionization mass spectrometry of oligonucleotides.用于寡核苷酸基质辅助激光解吸/电离质谱分析的多胺共基质
Rapid Commun Mass Spectrom. 1999;13(20):2014-21. doi: 10.1002/(SICI)1097-0231(19991030)13:20<2014::AID-RCM748>3.0.CO;2-C.
7
Nanoparticle microarray for high-throughput microbiome metabolomics using matrix-assisted laser desorption ionization mass spectrometry.基于基质辅助激光解吸电离质谱的高通量微生物组代谢组学用纳米颗粒微阵列。
Anal Bioanal Chem. 2019 Jan;411(1):147-156. doi: 10.1007/s00216-018-1436-5. Epub 2018 Oct 30.
8
Lipid fingerprinting of gram-positive lactobacilli by intact--matrix-assisted laser desorption/ionization mass spectrometry using a proton sponge based matrix.基于质子海绵基质的全基质辅助激光解吸电离质谱对革兰氏阳性乳杆菌的脂质指纹分析。
Rapid Commun Mass Spectrom. 2011 Jun 30;25(12):1757-64. doi: 10.1002/rcm.5035.
9
Matrix-assisted laser desorption/ionization matrices for negative mode metabolomics.用于负离子模式代谢组学的基质辅助激光解吸/电离基质
Eur J Mass Spectrom (Chichester). 2013;19(1):39-47. doi: 10.1255/ejms.1209.
10
Aggregation-induced emission compounds as new assisted matrices for laser desorption/ionization time-of-flight mass spectrometry.聚集诱导发射化合物作为新型辅助基质用于激光解吸/电离飞行时间质谱分析。
Anal Chim Acta. 2015 Jan 1;853:375-383. doi: 10.1016/j.aca.2014.09.047. Epub 2014 Oct 8.

引用本文的文献

1
Identification of Plant Compounds with Mass Spectrometry Imaging (MSI).利用质谱成像（MSI）鉴定植物化合物
Metabolites. 2024 Jul 30;14(8):419. doi: 10.3390/metabo14080419.
2
Synthesis of Functionalized Six-Membered-Ring Azahelicenes.功能化六元环氮杂薁的合成。
Molecules. 2022 Apr 14;27(8):2522. doi: 10.3390/molecules27082522.
3
Acid/base-triggered switching of circularly polarized luminescence and electronic circular dichroism in organic and organometallic helicenes.有机和有机金属螺旋烯中酸/碱触发的圆偏振发光和电子圆二色性的切换
Chemistry. 2015 Jan 19;21(4):1673-81. doi: 10.1002/chem.201405176. Epub 2014 Nov 21.