Frerot Eric, Bagnoud Alain, Cicchetti Esmeralda
Analytical Innovation Group, Corporate R&D Division, Firmenich S.A. 1, Route des Jeunes, 1211 Geneva 8 (Switzerland).
Chempluschem. 2014 Jan;79(1):77-82. doi: 10.1002/cplu.201300234. Epub 2013 Oct 11.
A sensitive analytical method for the quantification of malodourous hydrogen sulfide (H S) and methanethiol (CH SH) was developed and validated. The method consisted of solid-phase microextraction with concomitant in-fibre derivatisation of the mercaptan using N-ethylmaleimide. The adducts were analysed by GC-MS using a triple quadrupole in the selected reaction monitoring mode. The limits of detection of solutions of H S and CH SH in water were 100 and 10 ng L , respectively, below their odour-perception thresholds. The analytical method was used to show the scavenging effect of 1,2-benzisothiazol-3(2H)-one (Proxel) and 2-methyl-4-isothiazolinone. The mechanism by which H S and CH SH are trapped with Proxel was studied by ultraperformance liquid chromatography (UPLC)-MS.
开发并验证了一种用于定量恶臭硫化氢（H₂S）和甲硫醇（CH₃SH）的灵敏分析方法。该方法包括固相微萃取以及使用N - 乙基马来酰亚胺对硫醇进行纤维内衍生化。通过气相色谱 - 质谱联用仪在选择反应监测模式下使用三重四极杆对加合物进行分析。水中H₂S和CH₃SH溶液的检测限分别为100和10 ng·L⁻¹，低于它们的气味感知阈值。该分析方法用于展示1,2 - 苯并异噻唑 - 3(2H) - 酮（Proxel）和2 - 甲基 - 4 - 异噻唑啉 - 酮的清除效果。通过超高效液相色谱（UPLC） - 质谱联用仪研究了Proxel捕获H₂S和CH₃SH的机制。
