用于双链 DNA 序列特异性检测的组装依赖性荧光增强核酸
Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA.
作者信息
Doluca Osman, Hale Tracy K, Edwards Patrick J B, González Carlos, Filichev Vyacheslav V
机构信息
College of Sciences, Institute of Fundamental Sciences, Massey University, Private Bag 11-222, 4442 Palmerston North (New Zealand), Fax: (+64) 6-3505682.
International Burch University, Francuske Revolucije, 71210 Sarajevo (Bosnia and Herzegovina).
出版信息
Chempluschem. 2014 Jan;79(1):2. doi: 10.1002/cplu.201300369. Epub 2013 Dec 4.
Invited for this month's cover is the group of Dr. Vyacheslav V. Filichev from Massey University, New Zealand and a collaborator from the Instituto de Química Física Rocasalano, CSIC, Spain. The cover picture shows how a DNA strand that forms a highly stable G-quadruplex can be converted into an efficient DNA triplex-forming oligonucleotide by incorporating a pyrene intercalator into the sequence. Read the full text of the article at 10.1002/cplu.201300310.
本期封面文章的受邀作者是来自新西兰梅西大学的维亚切斯拉夫·V·菲利切夫博士团队以及来自西班牙国家研究委员会罗卡萨拉诺物理化学研究所的一位合作者。封面图片展示了一条形成高度稳定G-四链体的DNA链如何通过在序列中引入芘嵌入剂而转化为一种高效的形成DNA三链体的寡核苷酸。可登录10.1002/cplu.201300310阅读该文章全文。
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